Hycodan (Hydrocodone Bitartrate and Homatropine Methylbromide) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Hycodan

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HYCODAN®
(hydrocodone bitartrate and homatropine methylbromide) Tablets And Oral Solution

DRUG DESCRIPTION

HYCODAN (hydrocodone bitartrate and homatropine methylbromide) contains hydrocodone (dihydrocodeinone) bitartrate, a semisynthetic centrally-acting opioid antitussive. Homatropine methylbromide is included in a subtherapeutic amount to discourage deliberate overdosage.

Each HYCODAN (hydrocodone bitartrate and homatropine methylbromide) tablet or teaspoonful (5 mL) contains:

Hydrocodone Bitartrate, USP.....................5 mg
Homatropine Methylbromide, USP..................1.5 mg

HYCODAN (hydrocodone bitartrate and homatropine methylbromide) tablets also contain: calcium phosphate dibasic, colloidal silicon dioxide, lactose, magnesium stearate, starch and stearic acid.

HYCODAN (hydrocodone bitartrate and homatropine methylbromide) oral solution also contains: caramel coloring, FD&C Red 40, liquid sugar, methylparaben, propylparaben, sorbitol solution and wild cherry imitation flavor. The hydrocodone component is 4,5α-epoxy-3-methoxy-17-methylmorphinan-6-one tartrate (1:1) hydrate (2:5), a fine white crystal or crystalline powder, which is derived from the opium alkaloid, thebaine, has a molecular weight of (494.50), and may be represented by the following structural formula:

Hydrocodone Bitartrate Structural Formula Illustration

Homatropine Methylbromide Structural Formula Illustration

Homatropine methylbromide is 8-Azoniabicyclo [3.2.1]octane,3-[(hydroxyphenyl-acetyl)oxy]-8,8-dimethyl-,bromide, endo-; a white crystal or fine white crystalline powder, with a molecular weight of (370.29).

What are the possible side effects of homatropine and hydrocodone (Hycodan, Hydromet, Tussigon)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using homatropine and hydrocodone and call your doctor at once if you have any of these serious side effects:

painful urination;
urinating less than usual or not at all;
extreme drowsiness or weakness;
feeling like you might pass out;
weak or shallow breathing, or breathing that...

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What are the precautions when taking hydrocodone bitartrate and homatropine methylbromide (Hycodan)?

Before taking this medication, tell your doctor or pharmacist if you are allergic to hydrocodone; or to homatropine; or to other narcotic medications (e.g., codeine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: adrenal gland problems (e.g., Addison's disease), abdominal problems (e.g., chronic constipation, gallbladder disease, ileus, pancreatitis), breathing problems (e.g., asthma, chronic obstructive pulmonary disease-COPD, hypoxia, emphysema, intoxication with medications that can cause drowsiness or slow/shallow breathing), brain disorders (e.g.,...

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Last reviewed on RxList: 3/19/2009
This monograph has been modified to include the generic and brand name in many instances.