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How Supplied


HYCOTUSS (hydrocodone bitartrate and guaifenesin) Expectorant Syrup is indicated for the symptomatic relief of irritating nonproductive cough associated with upper and lower respiratory tract congestion.


Usual Adult Dose: One teaspoonful (5 mL) after meals and at bedtime, not less than 4 hours apart (not to exceed 6 teaspoonfuls in a 24 hour period). Treatment should be initiated with one teaspoonful and subsequent doses, up to a maximum single dose of 3 teaspoonfuls, adjusted if required.

Usual Children's Dose:

Over 12 years: Initial dose 1 teaspoonful; maximum single dose, 2 teaspoonfuls.

6 to 12 years: Initial dose 1/2 teaspoonful; maximum single dose, 1 teaspoonful.


HYCOTUSS (hydrocodone bitartrate and guaifenesin) Expectorant Syrup is available as an orange-colored, butterscotch flavored syrup in bottles as follows:

16 fl oz (473 mL)........................NDC 63481-235-16

Store at controlled room temperature between 20° -25° C (68° -77° F). [See USP] Store and dispense in a tight, light-resistant container as described in the U.S.P.

Manufactured for: Endo Pharmaceuticals Inc. Chadds Ford, PA 19317. Manufactured by: Pharmaceutical Associates, Inc. Greenville, SC 29605. R02/04. FDA Rev date: n/a

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 9/11/2008

How Supplied

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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