"In women at high risk for breast cancer, a long-term drug treatment can cut the risk of developing the disease in half. Researchers supported by the National Institutes of Health have now identified two gene variants that may predict which wom"...
Acute mucocutaneous toxicity has been reported in patients receiving hydroxyurea at dosages several times the therapeutic dose. Soreness, violet erythema, edema on palms and soles followed by scaling of hands and feet, severe generalized hyperpigmentation of the skin, and stomatitis have also been observed.
Hydroxyurea is contraindicated in patients with marked bone marrow depression, i.e., leukopenia ( < 2500 WBC) or thrombocytopenia ( < 100,000), or severe anemia.
HYDREA (hydroxyurea) is contraindicated in patients who have demonstrated a previous hypersensitivity to hydroxyurea or any other component of its formulation.
Last reviewed on RxList: 6/23/2010
This monograph has been modified to include the generic and brand name in many instances.
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