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HYLENEX (hyaluronidase human injection) is contraindicated in patients with known hypersensitivity to hyaluronidase or any of the excipients in HYLENEX (hyaluronidase human injection) . A preliminary skin test for hypersensitivity to HYLENEX recombinant (hyaluronidase human injection) can be performed. The skin test is made by an intradermal injection of approximately 0.02 mL (3 Units) of a 150 Unit/mL solution. A positive reaction consists of a wheal with pseudopods appearing within 5 minutes and persisting for 20 to 30 minutes and accompanied by localized itching. Transient vasodilation at the site of the test, i.e., erythema, is not a positive reaction.
Last reviewed on RxList: 12/29/2009
This monograph has been modified to include the generic and brand name in many instances.
Additional Hylenex Information
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