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Hypertonic Saline

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Hypertonic Saline

Hypertonic Saline Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 8/2/2015

Hypertonic Saline 3% and 5% Sodium Chloride Injection is an electrolyte and fluid replenisher used as a source of water and electrolytes. Hypertonic saline 3% and 5% sodium chloride is available in generic form. Common side effects of hypertonic saline 3% and 5% sodium chloride include fever, infection at injection site or redness/red streaking and swelling from the site of infection.

Dosage of Hypertonic Saline is dependent upon the age, weight, and clinical condition of the patient as well as laboratory determinations. Other drugs may affect Hypertonic Saline. Tell your doctor about all the prescription and over-the-counter medications and supplements you use. Hypertonic Saline should be given to a pregnant woman only if prescribed. Consult your doctor before breast-feeding.

Our Hypertonic Saline 3% and 5% Sodium Chloride Injection Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Hypertonic Saline FDA Prescribing Information: Side Effects
(Adverse Reactions)


Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia.

If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures, and save the remainder of the fluid for examination if deemed necessary.

Read the entire FDA prescribing information for Hypertonic Saline (3% and 5% Sodium Chloride Injection)

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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