"The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has recommended the marketing of selexipag (Uptravi, Actelion Registration Ltd) for the treatment of adults with pulmonary arterial hypertension (PAH)./"...
HYTRIN (terazosin hydrochloride), an alpha-1-selective adrenoceptor blocking agent, is a quinazoline derivative represented by the following chemical name and structural formula:
(RS)-Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetra-hydro-2-furanyl)carbonyl]-, monohydrochloride, dihydrate.
Terazosin hydrochloride is a white, crystalline substance, freely soluble in water and isotonic saline and has a molecular weight of 459.93. HYTRIN tablets (terazosin hydrochloride tablets) for oral ingestion are supplied in four dosage strengths containing terazosin hydrochloride equivalent to 1 mg, 2 mg, 5 mg, or 10 mg of terazosin.
1 mg tablet: corn starch, lactose, magnesium stearate, povidone and talc.
2 mg tablet: corn starch, FD&C Yellow No. 6, lactose, magnesium stearate, povidone and talc.
5 mg tablet: corn starch, iron oxide, lactose, magnesium stearate, povidone and talc.
10 mg tablet: corn starch, D&C Yellow No. 10, FD&C Blue No. 2, lactose, magnesium stearate, povidone and talc.
What are the possible side effects of terazosin (Hytrin)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- fast or pounding heartbeats or fluttering in your chest;
- feeling like you might pass out;
- swelling in your hands, ankles, or feet; or
- penis erection that is painful or lasts 4 hours or longer.
Less serious side effects may include:
- mild dizziness;
- weakness, drowsiness;
What are the precautions when taking terazosin hcl (Hytrin)?
Before taking terazosin, tell your doctor or pharmacist if you are allergic to it; or to other alpha blockers such as doxazosin or prazosin; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure/fainting, certain eye problems (cataracts, glaucoma).
This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. You should avoid driving or hazardous tasks for 12 hours after the first dose, after your dose is increased, and when...
Last reviewed on RxList: 12/15/2010
This monograph has been modified to include the generic and brand name in many instances.
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