In this Article

• What is hydrochlorothiazide and losartan (Hyzaar)?
• What are the possible side effects of hydrochlorothiazide and losartan (Hyzaar)?
• What is the most important information I should know about hydrochlorothiazide and losartan (Hyzaar)?
• What should I discuss with my healthcare provider before taking hydrochlorothiazide and losartan (Hyzaar)?
• How should I take hydrochlorothiazide and losartan (Hyzaar)?
• What happens if I miss a dose (Hyzaar)?
• What happens if I overdose (Hyzaar)?
• What should I avoid while taking hydrochlorothiazide and losartan (Hyzaar)?
• What other drugs will affect hydrochlorothiazide and losartan (Hyzaar)?
• Where can I get more information?

What should I discuss with my healthcare provider before taking hydrochlorothiazide and losartan (Hyzaar)?

You should not use this medication if you are allergic to hydrochlorothiazide or losartan, or if you are unable to urinate.

To make sure you can safely take hydrochlorothiazide and losartan, tell your doctor if you have any of these other conditions:

• kidney disease;
• liver disease;
• congestive heart failure;
• glaucoma;
• asthma;
• low or high levels of potassium in your blood;
• gout;
• lupus;
• diabetes; or
• an allergy to sulfa drugs or penicillin.

FDA pregnancy category D. Do not use hydrochlorothiazide and losartan if you are pregnant. Stop using this medication and tell your doctor right away if you become pregnant. Losartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control while taking hydrochlorothiazide and losartan.

It is not known whether hydrochlorothiazide and losartan passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take hydrochlorothiazide and losartan (Hyzaar)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

Take this medication with a full glass (8 ounces) of water.

Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medication, which can lead to severely low blood pressure or a serious electrolyte imbalance.

Your blood pressure will need to be checked often. Your kidney function may also need to be tested. Visit your doctor regularly.

Hydrochlorothiazide can interfere with the results of a thyroid test. Tell any doctor who treats you that you are using this medication.

If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Store at room temperature away from moisture and heat.