February 10, 2016
Recommended Topic Related To:

Ic-Green

"The US Food and Drug Administration (FDA) today approved asfotase alfa (Strensiq, Alexion Pharmaceuticals) as the first-ever therapy for patients who develop hypophosphatasia, a rare metabolic bone disorder, in childhood.

Cau"...

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Ic-Green

Overdosage
Contraindications

OVERDOSE

There are no data available describing the signs, symptoms, or la boratory findings accompanying overdosage. The LD50 after I.V. administration ranges between 60 and 80 mg/kg in mice, 50 and 70 mg/kg in rats and 50 and 80 mg/kg in rabbits. Based on body surface area, these doses are 2.4 to 13-fold the maximum recommended human (MRHD) dose of 2 mg/kg for indicator-dilution studies, 10 to 52-fold the MRHD of 0.5 mg/kg for hepatic-function studies, and 7 to 39-fold the MRHD of 0.67 mg/kg for ophthalmic angiography studies.

CONTRAINDICATIONS

IC-GREEN™ contains sodium iodide and should be used with caution in patients who have a history of allergy to iodides because of the risk of anaphylaxis.

This monograph has been modified to include the generic and brand name in many instances.

Last reviewed on RxList: 10/19/2015

Overdosage
Contraindications

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