"SILVER SPRING, MD ‚Ä” Using the antiplatelet clopidogrel with aspirin for over a year doesn't increase or decrease risk of overall death in patients with CHD or who are at risk for developing the disease‚Ä”and it doesn't change the risk of cancer dea"...
There are no data available describing the signs, symptoms, or la boratory findings accompanying overdosage. The LD50 after I.V. administration ranges between 60 and 80 mg/kg in mice, 50 and 70 mg/kg in rats and 50 and 80 mg/kg in rabbits. Based on body surface area, these doses are 2.4 to 13-fold the maximum recommended human (MRHD) dose of 2 mg/kg for indicator-dilution studies, 10 to 52-fold the MRHD of 0.5 mg/kg for hepatic-function studies, and 7 to 39-fold the MRHD of 0.67 mg/kg for ophthalmic angiography studies.
Last reviewed on RxList: 10/19/2015
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