July 29, 2016

Idebenone

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What other names is Idebenone known by?

2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone, Hydroxydecyl Benzoquinone, Idebenona, Idébénone.

What is Idebenone?

Idebenone is a man-made product similar to coenzyme Q-10.

Idebenone is used for Alzheimer's disease, liver disease, and heart disease; as well as a number of inherited disorders including Leber's disease (an eye condition), mitochondrial encephalomyopathies (nerve and muscle disorders), and Friedreich's ataxia (a nervous system disorder that worsens over time, producing gait and speech problems, and eventually leading toward heart disease and diabetes).

Possibly Effective for...

  • Treating Alzheimer's disease. There's some evidence that taking idebenone slows the decline of thinking skills in people with Alzheimer's disease. Idebenone appears most effective in patients with moderately severe Alzheimer's disease.

Insufficient Evidence to Rate Effectiveness for...

  • Friedreich's ataxia (an inherited progressive condition affecting the nerves that can lead to heart disease and diabetes). Some developing research suggests that taking idebenone may help control heart damage associated with Friedreich's ataxia. But other research hasn't shown this benefit. Idebenone does not appear to slow the progression of this condition.
  • Mitochondrial encephalomyopathies (a group of disorders that lead to muscle and nervous system problems). There is some research that suggests that taking idebenone might reduce symptoms in patients with some of these conditions.
  • Other conditions.
More evidence is needed to rate the effectiveness of idebenone for these uses.

Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).


Therapeutic Research Faculty copyright

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