In this Article

• What is sumatriptan injection (Imitrex Injection)?
• What are the possible side effects of sumatriptan injection (Imitrex Injection)?
• What is the most important information I should know about sumatriptan injection (Imitrex Injection)?
• What should I discuss with my health care provider before using sumatriptan injection (Imitrex Injection)?
• How should I use sumatriptan injection (Imitrex Injection)?
• What happens if I miss a dose (Imitrex Injection)?
• What happens if I overdose (Imitrex Injection)?
• What should I avoid while using sumatriptan injection (Imitrex Injection)?
• What other drugs will affect sumatriptan injection (Imitrex Injection)?
• Where can I get more information?

What should I discuss with my health care provider before using sumatriptan injection (Imitrex Injection)?

You should not use this medication if you are allergic to sumatriptan, or if you have:

• coronary heart disease, angina (chest pain), blood circulation problems, lack of blood supply to the heart;
• a history of heart disease, heart attack, or stroke, including "mini-stroke";
• severe or uncontrolled high blood pressure;
• severe liver disease;
• ischemic bowel disease; or
• a headache that seems different from your usual migraine headaches.

Do not use sumatriptan if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days.

To make sure you can safely use sumatriptan, tell your doctor if you have any of these other conditions:

• liver disease;
• kidney disease;
• epilepsy or other seizure disorder;
• high blood pressure, a heart rhythm disorder; or
• coronary heart disease (or risk factors such as diabetes, menopause, smoking, being overweight, having high cholesterol, having a family history of coronary artery disease, being older than 40 and a man, or being a woman who has had a hysterectomy).

FDA pregnancy category C. It is not known whether sumatriptan will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Your name may need to be listed on a sumatriptan pregnancy registry when you start using this medication.

Sumatriptan can pass into breast milk and may harm a nursing baby. Do not breast-feed within 12 hours after using a sumatriptan injection. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.

This medicine should not be given to anyone under 18 or over 65 years of age.

How should I use sumatriptan injection (Imitrex Injection)?

Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Overuse of migraine headache medicine can actually make your headaches worse.

Sumatriptan is injected under the skin. You may be shown how to use injections at home. Do not self inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Use sumatriptan as soon as you notice headache symptoms, or after an attack has already begun.

Your doctor may want to give your first dose of this medicine in a hospital or clinic setting to see if you have any serious side effects.

Sumatriptan injection comes in a vial (bottle), in a prefilled cartridge to be loaded into an auto-injector syringe (Imitrex Statdose), or in a needle-free injector device (Sumavel DosePro). Each vial, cartridge, or needle-free device is for one use only.

After using an injection: If your headache does not completely go away after the injection, call your doctor before using a second sumatriptan injection. If your headache goes away and then comes back, you may use a second injection if it has been at least one hour since your first injection. Do not use more than two (2) injections in 24 hours. If your symptoms do not improve, contact your doctor before using any more injections.

Store at room temperature away from moisture, heat, and light. Throw away any unused medicine after the expiration date on the label has passed.