Inderal LA (Propranolol) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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May 26, 2012

Inderal LA

Atrial Fibrillation »

What is atrial fibrillation?

Atrial fibrillation (AF) is the most common, abnormal rhythm of the heart.

The heart contracts (beats) and pumps blood with a regular rhythm, for example, at a rate of 60 beats per minute there is a beat every second. The heart may beat faster or slower with a shorter or longer interval between beats, but at any one rate the interval between beats is constant. This regular rhythm occurs as a result of regular electrical discharges (currents) that travel through the heart and cause the muscle of the heart to contract. In atrial fibrillation, the electrical discharges are irregular and rapid and, as a result, the heart beats irregularly and, usually, rapidly.

Atrial fibrillation is common; half a million new cases are diagnosed yearly in the U.S., and billions of dollars are spent annually on its diagnosis and treatment.

What causes atrial fibrillation?

Normal function of the he...

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Inderal® LA
(propranolol hydrochloride) Long-Acting Capsules

DRUG DESCRIPTION

Inderal® (propranolol hydrochloride) is a synthetic beta-adrenergic receptor-blocking agent chemically described as 2-Propanol, l-[(l-methylethyl)amino]-3-(l-naphthalenyloxy)-, hydrochloride,(±)-. Its molecular and structural formulae are:

Inderal® LA
(propranolol hydrochloride) Long-Acting Capsules Structural Formula Illustration

C₁₆H₂₁NO₂ · HCl

Propranolol hydrochloride is a stable, white, crystalline solid which is readily soluble in water and ethanol. Its molecular weight is 295.80.

Inderal LA is formulated to provide a sustained release of propranolol hydrochloride. Inderal LA (propranolol) is available as 60 mg, 80 mg, 120 mg, and 160 mg capsules for oral administration.

The inactive ingredients contained in Inderal LA (propranolol) capsules are: cellulose, ethylcellulose, gelatin capsules, hypromellose, and titanium dioxide. In addition, Inderal LA (propranolol) 60 mg, 80 mg, and 120 mg capsules contain D&C Red No. 28 and FD&C Blue No. 1; Inderal LA (propranolol) 160 mg capsules contain FD&CBlueNo. 1.

These capsules comply with USP Dissolution Test 1.

What are the possible side effects of propranolol (Inderal, Inderal LA, InnoPran XL)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

fast, slow, or uneven heartbeats;
feeling light-headed, fainting;
feeling short of breath, even with mild exertion;
swelling of your ankles or feet;
fever, sore throat, and headache with a severe blistering, peeling, and red...

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What are the precautions when taking propranolol (Inderal LA)?

Before taking propranolol, tell your doctor or pharmacist if you are allergic to it; or if you have had a serious reaction to other beta blockers (e.g., metoprolol); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: certain types of heart rhythm problems (sinus bradycardia, second- or third-degree atrioventricular block), severe heart failure, asthma.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: other breathing problems (e.g., bronchitis,...

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Last reviewed on RxList: 10/12/2010
This monograph has been modified to include the generic and brand name in many instances.