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Inderal LA

Last reviewed on RxList: 9/6/2016
Inderal LA Side Effects Center

Last reviewed on RxList 11/11/2016

Inderal LA (propranolol hydrochloride) is a beta-blocker used to treat tremors, angina (chest pain), hypertension (high blood pressure), heart rhythm disorders, and other heart or circulatory conditions. Inderal LA is also used to treat or prevent heart attack, and to reduce the severity and frequency of migraine headaches. Inderal LA is available in generic form. Common side effects of Inderal LA include:

  • dizziness,
  • lightheadedness, or
  • tiredness as your body adjusts to the medication.

Other side effects of Inderal LA include:

  • nausea,
  • vomiting,
  • stomach pain or cramps,
  • diarrhea,
  • constipation,
  • vision changes,
  • trouble sleeping (insomnia),
  • unusual dreams,
  • decreased sex drive,
  • impotence, or
  • difficulty having an orgasm.

Tell your doctor if you have unlikely but serious side effects of Inderal LA including:

  • shortness of breath,
  • blue fingers or toes,
  • swelling ankles or feet,
  • mental/mood changes (e.g., depression),
  • numbness or tingling of arms or legs,
  • very slow heartbeat,
  • fainting,
  • unexplained or sudden weight gain, or
  • increased thirst or urination.

The usual dosage of Inderal LA ranges from 80 to 160 mg once daily, depending on the condition being treated. Inderal LA may interact with clonidine, digitalis, dobutamine, haloperidol, isoproterenol, blood thinners, antidepressants, MAO inhibitors, aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs), doxazosin, prazosin, terazosin, heart medications, amiodarone, propafenone, quinidine, or ACE inhibitors. During pregnancy, Inderal LA should be used only when prescribed. Infants exposed to this medication during pregnancy may have low birth weight, low blood sugar, or slow breathing/heartbeat. This drug passes into breast milk. Consult your doctor before breastfeeding.

Our Inderal LA (propranolol hydrochloride) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Inderal LA Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • fast, slow, or uneven heartbeats;
  • feeling light-headed, fainting;
  • feeling short of breath, even with mild exertion;
  • swelling of your ankles or feet;
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • cold feeling in your hands and feet;
  • depression, confusion, hallucinations; or
  • severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Less serious side effects may include:

  • nausea, vomiting, diarrhea, constipation, stomach cramps;
  • decreased sex drive, impotence, or difficulty having an orgasm;
  • sleep problems (insomnia); or
  • tired feeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Inderal LA (Propranolol)

Inderal LA Professional Information

SIDE EFFECTS

The following adverse events were observed and have been reported in patients using propranolol.

Cardiovascular

Bradycardia; congestive heart failure; intensification of AV block; hypotension; paresthesia of hands; thrombocytopenic purpura; arterial insufficiency, usually of the Raynaud type.

Central Nervous System

Light-headedness; mental depression manifested by insomnia, lassitude, weakness, fatigue; catatonia; visual disturbances; hallucinations; vivid dreams; an acute reversible syndrome characterized by disorientation for time and place, short-term memory loss, emotional lability, slightly clouded sensorium, and decreased performance on neuropsychometrics. For immediate release formulations, fatigue, lethargy, and vivid dreams appear dose related.

Gastrointestinal

Nausea, vomiting, epigastric distress, abdominal cramping, diarrhea, constipation, mesenteric arterial thrombosis, ischemic colitis.

Allergic

Hypersensitivity reactions, including anaphylactic/anaphylactoid reactions; pharyngitis and agranulocytosis; erythematous rash; fever combined with aching and sore throat; laryngospasm; respiratory distress.

Respiratory

Bronchospasm.

Hematologic

Agranulocytosis, nonthrombocytopenic purpura, and thrombocytopenic purpura.

Autoimmune

Systemic lupus erythematosus (SLE).

Skin And Mucous Membranes

Stevens-Johnson Syndrome, toxic epidermal necrolysis, dry eyes, exfoliative dermatitis, erythema multiforme, urticaria, alopecia, SLE-like reactions, and psoriasisiform rashes. Oculomucocutaneous syndrome involving the skin, serous membranes, and conjunctivae reported for a beta-blocker (practolol) have not been associated with propranolol.

Genitourinary

Male impotence; Peyronie's disease.

Read the entire FDA prescribing information for Inderal LA (Propranolol)

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