April 30, 2017
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Inderide Patient Information including How Should I Take

What should I discuss with my doctor before taking hydrochlorothiazide and propranolol (Inderide)?

You should not use this medication if you are allergic to hydrochlorothiazide or propranolol, or if you have:

  • asthma;
  • severe or uncontrolled heart failure;
  • a heart condition called "sick sinus syndrome" or "AV block" (2nd or 3rd degree); or
  • if you are unable to urinate.

To make sure you can safely take hydrochlorothiazide and propranolol, tell your doctor if you have any of these other conditions:

  • congestive heart failure;
  • kidney disease;
  • liver disease (or cirrhosis);
  • glaucoma;
  • bronchospastic lung disease;
  • a thyroid disorder;
  • lupus;
  • gout;
  • diabetes; or
  • if you are allergic to sulfa drugs or penicillin.

FDA pregnancy category C. It is not known whether hydrochlorothiazide and propranolol will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Hydrochlorothiazide and propranolol can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take hydrochlorothiazide and propranolol (Inderide)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

Do not stop using hydrochlorothiazide and propranolol suddenly, or you could have a serious or life-threatening heart problem. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication.

Your blood pressure will need to be checked often. Your blood and urine may both be tested if you have been vomiting or are dehydrated. Visit your doctor regularly.

If you are diabetic, check your blood sugar carefully. Using propranolol can make it harder for you to tell when you have low blood sugar. Your insulin or diabetic medication needs may change while you are taking hydrochlorothiazide and propranolol. Talk with your doctor before changing any doses.

If you need surgery or medical tests, tell the doctor ahead of time that you are taking medication that contains hydrochlorothiazide. You may need to stop using the medicine for a short time.

Keep using hydrochlorothiazide and propranolol even if you feel fine. High blood pressure often has no symptoms.

Store this medication in a tightly closed container at room temperature, away from heat and moisture.

Side Effects Centers

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Get tips on handling your hypertension.