- What other names is Indole-3-carbinol known by?
- What is Indole-3-carbinol?
- How does Indole-3-carbinol work?
- Are there safety concerns?
- Are there any interactions with medications?
- Dosing considerations for Indole-3-carbinol.
Indole-3-carbinol is used for prevention of breast cancer, colon cancer, and other types of cancer. The National Institutes of Health (NIH) has reviewed indole-3-carbinol as a possible cancer preventive agent and is now sponsoring clinical research for breast cancer prevention.
Indole-3-carbinol is also used for fibromyalgia, tumors inside the voice box (laryngeal papillomatosis) caused by a virus, tumors inside the respiratory tract (respiratory papillomatosis) caused by a virus, abnormal cell growth in the cervix (cervical dysplasia), and systemic lupus erythematosus (SLE). Some people use indole-3-carbinol to balance hormone levels, "detoxify" the intestines and liver, and to support the immune system.
Possibly Effective for...
- Abnormal development and growth of cells of the cervix (cervical dysplasia).
Insufficient Evidence to Rate Effectiveness for...
- Respiratory papillomatosis. There is some evidence that long-term use of indole-3-carbinol might reduce tumor (papilloma) growth in patients with recurrent respiratory papillomatosis.
- Laryngeal papillomatosis.
- Prevention of breast cancer.
- Colon cancer.
- Systemic lupus erythematosus (SLE).
- Hormone imbalances.
- Other conditions.
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
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