Hypertension

Innopran XL (propranolol hydrochloride) is indicated in the management of hypertension; it may be used alone or in combination with other antihypertensive agents.

Innopran XL (propranolol hydrochloride) should be administered once daily at bedtime (approximately 10 p.m.) and should be taken consistently either on an empty stomach or with food. The starting dose is 80 mg but dosage should be individualized and titration may be needed to a dose of 120 mg. In the clinical trial, doses of Innopran XL above 120 mg had no additional effects on blood pressure (see CLINICAL PHARMACOLOGY, Pharmacodynamics and Clinical Effects). The time needed for full antihypertensive response is variable, but is usually achieved within 2 to 3 weeks.

Innopran XL (propranolol hydrochloride) Extended Release Capsules

Each gray/white capsule, imprinted with "80", 2 segmented bands, "InnoPran XL", and the Reliant logo, contains 80 mg of propranolol hydrochloride in bottles of 30 (NDC 0173-0790-01), bottles of 100 (NDC 0173-0790-02).

Each gray/off-white capsule, imprinted with "120", 3 segmented bands, "InnoPran XL", and the Reliant logo, contains 120 mg of propranolol hydrochloride in bottles of 30 (NDC 0173-0791-01), and bottles of 100 (NDC 0173-0791-02).

Store at 25°C (77°F); excursions permitted to 15 and 30°C (59 and 86°F) [see USP Controlled Room Temperature] in a tightly closed container.

Manufacturer details: n/a

Last reviewed on RxList: 2/3/2011
This monograph has been modified to include the generic and brand name in many instances.