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InnoPran XL

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InnoPran XL

Overdosage
Contraindications

OVERDOSE

Most overdoses of propranolol are mild and respond to supportive care.

Propranolol is not significantly dialyzable.

Hypotension and bradycardia have been reported following propranolol overdose and should be treated appropriately. Glucagon can exert potent inotropic and chronotropic effects and may be particularly useful for the treatment of hypotension or depressed myocardial function after a propranolol overdose.

Glucagon should be administered as 50-150 mcg/kg intravenously followed by continuous drip of 1-5 mg/hour for positive chronotropic effect. Isoproterenol, dopamine or phosphodiesterase inhibitors may also be useful. Epinephrine, however, may provoke uncontrolled hypertension. Bradycardia can be treated with atropine or isoproterenol. Serious bradycardia may require temporary cardiac pacing.

Monitor the electrocardiogram, pulse, blood pressure, neurobehavioral status and intake and output balance. Isoproterenol and aminophylline may be used for bronchospasm.

CONTRAINDICATIONS

INNOPRAN XL is contraindicated in patients with:

Last reviewed on RxList: 12/23/2013
This monograph has been modified to include the generic and brand name in many instances.

Overdosage
Contraindications
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InnoPran XL - User Reviews

InnoPran XL User Reviews

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