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Inspra

What is a stroke?

Brain cell function requires a constant delivery of oxygen and glucose from the bloodstream. A stroke, or cerebrovascular accident (CVA), occurs when blood supply to part of the brain is disrupted, causing brain cells to die. Blood flow can be compromised by a variety of mechanisms.

Blockage of an artery

  • Narrowing of the small arteries within the brain can cause a lacunar stroke, (lacune means "empty space"). Blockage of a single arteriole can affect a tiny area of brain causing that tissue to die (infarct).
  • Hardening of the arteries (atherosclerosis) leading to the brain. There are four major blood vessels that supply the brain with blood. The anterior circulation of the brain that controls most motor  activity, sensation, thought, speech, and emotion is supplied by the carotid arteries. The posterior circulation, which supplies the brainstem and the cer...

Inspra

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Inspra Drug Center

Medical Editor: John P. Cunha, DO, FACOEP

Inspra (eplerenone) is used to treat congestive heart failure after a heart attack, and is also used to treat high blood pressure (hypertension). It is an aldosterone receptor blocker, which is an antihypertensive. This medication is available in generic form. Common side effects include headache, dizziness, diarrhea, stomach pain, nausea, cough or flu-like symptoms (such as fever, chills, unusual tiredness).

Treatment with Inspra is initiated at 25 mg once daily and adjusted to the recommended dose of 50 mg once daily, preferably within 4 weeks as tolerated by the patient. Inspra may interact with lithium, other blood pressure medications, antibiotics, antifungals, ACE inhibitors, NSAIDs (non-steroidal anti-inflammatory drugs), HIV/AIDS medicines, or antidepressants. Tell your doctor all medications you are taking. During pregnancy, Inspra should be used only when prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breast-feeding.

Our Inspra (eplerenone) Drug Center provides a comprehensive view of available drug information as well as related drugs, user reviews, supplements, and diseases and conditions articles.

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Inspra Prescribing Information: Indications & Dosage

Patient Selection Considerations

Serum potassium levels should be measured before initiating INSPRA (eplerenone) therapy, and INSPRA (eplerenone) should not be prescribed if serum potassium is > 5.5 mEq/L. [See CONTRAINDICATIONS].

Congestive Heart Failure Post-Myocardial Infarction

INSPRA (eplerenone) is indicated to improve survival of stable patients with left ventricular (LV) systolic dysfunction (ejection fraction 40%) and clinical evidence of congestive heart failure (CHF) after an acute myocardial infarction (MI).

Hypert...

Read the complete drug monograph for Inspra »

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Inspra Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have any of these serious side effects:

  • high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling); or
  • low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling).

Less serious side effects may include:

  • diarrhea, stomach pai...

Read the complete patient information for Inspra »

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Inspra Consumer Information: Uses

This medication is used alone or in combination with other medicines to treat high blood pressure. It works by blocking a chemical (aldosterone) in your body which in turn lowers the amount of sodium and water the body retains. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems. It is also used to treat congestive heart failure following a heart attack.

HOW TO USE: Take this medication by mouth, usually once or twice daily, with or without food, or as directed by your doctor. Use this medication regularly in order ...

Read the complete consumer information for Inspra »

What is Inspra Consumer Information?

Warnings - Uses - How to Use - Side Effects - Precautions - Drug Interactions and More

Inspra - User Reviews

Inspra User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Inspra sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Hypertension

Get tips on handling your hypertension.