Inspra (Eplerenone) Patient Information: Missed a Dose and What Should I Avoid at RxList

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May 27, 2012

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Stroke »

What is a stroke?

Brain cell function requires a constant delivery of oxygen and glucose from the bloodstream. A stroke, or cerebrovascular accident (CVA), occurs when blood supply to part of the brain is disrupted, causing brain cells to die. Blood flow can be compromised by a variety of mechanisms.

Blockage of an artery

Narrowing of the small arteries within the brain can cause a lacunar stroke, (lacune means "empty space"). Blockage of a single arteriole can affect a tiny area of brain causing that tissue to die (infarct).
Hardening of the arteries (atherosclerosis) leading to the brain. There are four major blood vessels that supply the brain with blood. The anterior circulation of the brain that controls most motor activity, sensation, thought, speech, and emotion is supplied by the carotid arteries. The posterior circulation, which supplies the brainstem and the cer...

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Inspra Patient Information including If I Miss a Dose

What happens if I miss a dose (Inspra)?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Inspra)?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include slow heart rate, weak pulse, muscle weakness, dizziness, or feeling like you might pass out.

What should I avoid while taking eplerenone (Inspra)?

Do not use salt substitutes or potassium supplements while taking eplerenone, unless your doctor has told you to.

What other drugs will affect eplerenone (Inspra)?

Many drugs can interact with eplerenone. Below is just a partial list. Tell your doctor if you are using:

lithium (Lithobid, Eskalith, others);
other blood pressure medications such as candesartan (Atacand), eprosartan (Teveten), irbesartan (Avapro), losartan (Cozaar), olmesartan (Benicar), telmisartan (Micardis), or valsartan (Diovan);
an antibiotic such as clarithromycin (Biaxin), erythromycin (E.E.S., E-Mycin, Ery-Tab, Erythrocin), or troleandomycin (Tao);
an antifungal medication such as fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral);
an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik);
an NSAID (non-steroidal anti-inflammatory drugs) such as ibuprofen (Motrin, Advil), diclofenac (Voltaren), etodolac (Lodine), indomethacin (Indocin), ketoprofen (Orudis), naproxen (Aleve, Naprosyn), and others; or
HIV/AIDS medicine such as nelfinavir (Viracept) or ritonavir (Norvir);
an "SSRI" antidepressant such as fluoxetine (Prozac), fluvoxamine (Luvox), or paroxetine (Paxil); or
a tricyclic antidepressant such as amitriptyline (Elavil, Etrafon), clomipramine (Anafranil), doxepin (Sinequan), imipramine (Janimine, Tofranil), and others.

This list is not complete and there may be other drugs that can interact with eplerenone. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about eplerenone.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others and use this medication only for the condition prescribed.

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