"The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has recommended the marketing of selexipag (Uptravi, Actelion Registration Ltd) for the treatment of adults with pulmonary arterial hypertension (PAH)./"...
Inspra Patient Information Including Side Effects
Brand Names: Inspra
Generic Name: eplerenone (Pronunciation: ep LER e none)
- What is eplerenone (Inspra)?
- What are the possible side effects of this drug (Inspra)?
- What is the most important information I should know about eplerenone (Inspra)?
- What should I discuss with my healthcare provider before taking eplerenone (Inspra)?
- How should I take eplerenone (Inspra)?
- What happens if I miss a dose (Inspra)?
- What happens if I overdose (Inspra)?
- What should I avoid while taking eplerenone (Inspra)?
- What other drugs will affect eplerenone (Inspra)?
- Where can I get more information?
What is eplerenone (Inspra)?
Eplerenone blocks the actions of the hormone aldosterone in the body. Aldosterone is important for the regulation of blood pressure.
Eplerenone is used to treat congestive heart failure after a heart attack. Eplerenone is also used to treat high blood pressure (hypertension).
Eplerenone may also be used for purposes not listed in this medication guide.
Eplerenone 25 mg-APO
round, yellow, imprinted with APO, EP 25
Eplerenone 50 mg-APO
round, yellow, imprinted with APO, EP 50
Inspra 25 mg
diamond, yellow, imprinted with Pfizer, NSR 25
Inspra 50 mg
diamond, yellow, imprinted with Pfizer, NSR 50
What are the possible side effects of this drug (Inspra)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe stomach pain; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
- high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling); or
- low potassium (confusion, uneven heart rate, extreme thirst, increased urination, leg discomfort, muscle weakness or limp feeling).
Less serious side effects may include:
- diarrhea, stomach pain;
- tired feeling;
- fever, chills, body aches, flu symptoms;
- vaginal bleeding; or
- breast swelling or tenderness.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the Inspra (eplerenone) Side Effects Center for a complete guide to possible side effects
What is the most important information I should know about eplerenone (Inspra)?
You may not be able to take this medication if you have severe kidney disease, high potassium levels in your blood, or type 2 diabetes with protein in your urine.
You also may not be able to take eplerenone if you are also taking ketoconazole (Nizoral), itraconazole (Sporanox), nefazodone, clarithromycin (Biaxin), nelfinavir (Viracept), ritonavir (Norvir, Kaletra), or troleandomycin (Tao).
Before taking eplerenone, tell your doctor if you have kidney or liver disease, high cholesterol, or high triglycerides.
Do not use salt substitutes or potassium supplements while taking eplerenone, unless your doctor has told you to.
To be sure this medication is helping your condition and is not causing harmful effects, your blood pressure will need to be checked on a regular basis. Your potassium levels will also need to be checked with frequent blood tests. Visit your doctor regularly.
If you are being treated for high blood pressure, keep using this medication even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Additional Inspra Information
- Inspra Drug Interactions Center: eplerenone oral
- Inspra Side Effects Center
- Inspra Overview including Precautions
- Inspra FDA Approved Prescribing Information including Dosage
Inspra - User Reviews
Inspra User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Get tips on handling your hypertension.