Integrilin (Eptifibatide) Patient Information: How Should I Take the Drug at RxList

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May 27, 2012

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Deep Vein Thrombosis (DVT) »

Introduction to deep vein thrombosis (DVT)

Arteries have thin muscles within their walls to be able to withstand the pressure of the heart pumping blood to the far reaches of the body. Veins don't have a significant muscle lining, and there is nothing pumping blood back to the heart except physiology. Blood returns to the heart because the body's large muscles squeeze the veins as they contract in their normal activity of moving the body. The normal activities of moving the body returns the blood back to the heart.

There are two types of veins in the leg; superficial veins and deep veins. Superficial veins lie just below the skin and are easily seen on the surface. Deep veins, as their name implies, are located deep within the muscles of the leg. Blood flows from the superficial veins into the deep venous system through small perforator veins. Superficial and perforator veins have one-way valves within them that allow blood to flow only in the direc...

Read the Deep Vein Thrombosis (DVT) article »

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Integrilin Patient Information including How Should I Take

What should I discuss with my health care provider before receiving eptifibatide (Integrilin)?

Do not receive this medication if you are allergic to eptifibatide, if you have or will soon receive treatment with similar medications such as abciximab (ReoPro) or tirofiban (Aggrastat), or if you have:

kidney disease (or if you are on dialysis);
a severe form of hypertension (high blood pressure);
a bleeding or blood clotting disorder, such as hemophilia or thrombocytopenia;
a history of blood clot in the brain (aneurysm);
if you have had a stroke or any type of bleeding within the past 30 days; or
if you have had any type of surgery, injury, or medical emergency within the past 6 weeks.

Before using eptifibatide, tell your doctor if you are allergic to any drugs

FDA Pregnancy Category B. Eptifibatide is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

It is not known whether eptifibatide passes into breast milk or if it could harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.

How is eptifibatide given (Integrilin)?

Eptifibatide is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting.

If you are receiving this injection during an angioplasty procedure, the medicine will be given throughout the entire procedure and for up to 24 hours after the procedure.

Eptifibatide is usually given continuously for up to 4 days.

Eptifibatide is sometimes given together with aspirin.

To be sure this medication is not causing harmful effects, your blood will need to be tested on a regular basis. Do not miss any scheduled visits to your doctor.

Because eptifibatide keeps your blood from coagulating (clotting) to prevent unwanted blood clots, it can also make it easier for you to bleed, even from a minor injury. Contact your doctor or seek emergency medical attention if you have bleeding that will not stop.

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