April 28, 2017
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Intelence Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking etravirine (Intelence)?

You should not take etravirine if you are allergic to it.

To make sure you can safely take etravirine, tell your doctor if you have any liver disease, including hepatitis B or C.

Etravirine must be taken in combination with other HIV medications. However, there are certain combinations of medicines that should not be used together with etravirine. Follow your doctor's dosing instructions very carefully.

You SHOULD NOT take etravirine together with:

  • delavirdine (Rescriptor);
  • efavirenz (Sustiva, Atripla);
  • nevirapine (Viramune);
  • rifabutin (Mycobutin), rifapentine (Priftin), or rifampin (Rifadin, Rifater, Rifamate, Rimactane);
  • rilpivirine (Edurant);
  • St. John's wort;
  • atazanavir (Reyataz) given with ritonavir (Norvir);
  • fosamprenavir (Lexiva) given with ritonavir (Norvir);
  • tipranavir (Aptivus) given with ritonavir (Norvir);
  • ritonavir (Norvir) in doses of more than 600 milligrams twice daily; or
  • seizure medications such as phenytoin (Dilantin), phenobarbital (Solfoton), or carbamazepine (Carbatrol, Equetro, Tegretol).

You MUST take etravirine together with ritonavir if you are also taking:

  • indinavir (Crixivan); or
  • nelfinavir (Viracept).

FDA pregnancy category B. Tell your doctor if you are pregnant or plan to become pregnant during treatment. HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of etravirine on the baby.

Women with HIV or AIDS should not breast-feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

How should I take etravirine (Intelence)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Etravirine must be taken in combination with other HIV medications. Follow your doctor's dosing instructions very carefully.

Etravirine works best if you take it after a meal. Do not take it on an empty stomach.

Do not crush, chew, or break an etravirine tablet. Swallow it whole with liquid such as water.

If you cannot swallow an etravirine tablet whole, place it into a glass of water and allow the tablet to disperse in the liquid. The tablet will not dissolve completely. Drink this mixture right away. To make sure you get the entire dose, add a little more liquid to the same glass, swirl gently and drink right away.

If a child is taking this medication, tell your doctor if the child has any changes in weight. Etravirine doses are based on weight in children.

Use etravirine regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.

To be sure this medication is helping your condition, your blood will need to be tested often. Visit your doctor regularly.

Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with the packet of moisture-absorbing preservative that comes with the medication.

Side Effects Centers

Intelence - User Reviews

Intelence User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Intelence sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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