In this Article

• What is etravirine (Intelence)?
• What are the possible side effects of etravirine (Intelence)?
• What is the most important information I should know about etravirine (Intelence)?
• What should I discuss with my healthcare provider before taking etravirine (Intelence)?
• How should I take etravirine (Intelence)?
• What happens if I miss a dose (Intelence)?
• What happens if I overdose (Intelence)?
• What should I avoid while taking etravirine (Intelence)?
• What other drugs will affect etravirine (Intelence)?
• Where can I get more information?

What should I discuss with my healthcare provider before taking etravirine (Intelence)?

You should not take etravirine if you are allergic to it.

To make sure you can safely take etravirine, tell your doctor if you have any liver disease, including hepatitis B or C.

You should not take etravirine together with:

• delavirdine (Rescriptor);
• efavirenz (Sustiva, Atripla);
• nevirapine (Viramune);
• rifapentine (Priftin), or rifampin (Rifadin, Rifater, Rifamate, Rimactane);
• St. John's wort;
• atazanavir (Reyataz) given with ritonavir (Norvir);
• fosamprenavir (Lexiva) given with ritonavir (Norvir);
• tipranavir (Aptivus) given with ritonavir (Norvir);
• ritonavir (Norvir) in doses of more than 600 milligrams twice daily; or
• seizure medications such as phenytoin (Dilantin), phenobarbital (Solfoton), or carbamazepine (Carbatrol, Tegretol).

You must take etravirine together with ritonavir if you are also taking:

• indinavir (Crixivan); or
• nelfinavir (Viracept).

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of etravirine on the baby.

Women with HIV or AIDS should not breast-feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.

How should I take etravirine (Intelence)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Etravirine must be taken in combination with other HIV medications. Follow your doctor's instructions.

Etravirine works best if you take it after a meal. Do not take it on an empty stomach.

If you cannot swallow an etravirine tablet whole, place it into a glass of water and allow the tablet to disperse in the liquid. The tablet will not dissolve completely. Drink this mixture right away. To make sure you get the entire dose, add a little more liquid to the same glass, swirl gently and drink right away.

Use etravirine regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.

To be sure this medication is helping your condition, your blood will need to be tested often. Visit your doctor regularly.

Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with the packet of moisture-absorbing preservative that comes with the medication.