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Intron A

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Intron A

Intron A

Intron A Patient Information Including Side Effects

Brand Names: Intron A

Generic Name: interferon alfa-2b (Pronunciation: IN ter FEAR on AL fa 2b)

What is interferon alfa-2b (Intron A)?

Interferon alfa-2b is made from human proteins. Interferons help the body fight viral infections.

Interferon alfa-2b is used to treat hairy cell leukemia, malignant melanoma, follicular lymphoma, Kaposi's sarcoma caused by AIDS, and certain types of genital warts. Interferon alfa-2b is also used to treat chronic hepatitis B or C.

Interferon alfa-2b is often used in combination with another drug called ribavirin (Rebetol). Some of the information in this medication guide applies to the use of both drugs in this combination.

Interferon alfa-2b may also be used for other purposes not listed in this medication guide.

What are the possible side effects of interferon alfa-2b (Intron A)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using interferon alfa-2b and call your doctor at once if you have a serious side effect such as:

  • severe depression, aggressive behavior, or thoughts of hurting yourself or others;
  • fast, slow, or uneven heart rate, feeling like you might pass out;
  • fever, chills, body aches, flu symptoms, pale skin, easy bruising or bleeding, unusual weakness;
  • vision or hearing problems;
  • urinating less than usual or not at all;
  • severe stomach pain, jaundice (yellowing of the skin or eyes);
  • cough with yellow or green mucus, feeling short of breath;
  • chest pain, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
  • sudden numbness or weakness, headache, confusion, or problems with speech or balance; or
  • a severe blistering, peeling, and red skin rash.

Less serious side effects may include:

  • dizziness, spinning sensation;
  • muscle pain, tired feeling;
  • nausea, vomiting, diarrhea, loss of appetite;
  • dry mouth, dry cough, sore throat, hair loss;
  • mild itching or skin rash; or
  • burning, bleeding, pain, itching, or skin changes where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the Intron A (interferon alfa-2b, recombinant for injection) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about interferon alfa-2b (Intron A)?

Interferon alfa-2b is often used in combination with another drug called ribavirin (Rebetol). Some of the information in this medication guide applies to the use of both drugs in this combination.

Interferon alfa-2b may be harmful to an unborn baby, or may cause a miscarriage. Do not use interferon alfa-2b if you are pregnant, especially if you also take ribavirin (Rebetol). Use 2 forms of effective birth control while you are using this drug combination and for at least 6 months after your treatment ends.

If a man fathers a child while using interferon alfa-2b and ribavirin, the baby may have birth defects. Use a condom to prevent pregnancy during your treatment and for at least 6 months after you stop using this drug combination..

You should not use interferon alfa-2b if you are allergic to interferons, or if you have autoimmune hepatitis, or severe liver problems from causes other than hepatitis B or C.

You should not use the combination of interferon alfa-2b and ribavirin if you have an allergy to either drug, or if you have severe kidney disease, a blood cell disorder, if you are pregnant, or if you are a man and your female sex partner is pregnant.

Side Effects Centers

Intron A - User Reviews

Intron A User Reviews

Now you can gain knowledge and insight about a drug treatment with Patient Discussions.

Here is a collection of user reviews for the medication Intron A sorted by most helpful. Patient Discussions FAQs

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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