Intuniv (guanfacine) Drug Information: Description, User Reviews, Drug Side Effects, Interactions

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February 10, 2012

Intuniv

Adult ADHD (Attention Deficit Hyperactivity Disorder) »

What Is Attention Deficit Hyperactivity Disorder (ADHD)?

Attention deficit hyperactivity disorder (ADHD) is one of the most well-recognized childhood developmental problems. This condition is characterized by inattention, hyperactivity and impulsiveness. It is now known that these symptoms continue into adulthood for about 60% of children with ADHD. That translates into 4% of the US adult population, or 8 million adults. However, few adults are identified or treated for adult ADHD.

ADHD in Adults

Adults with ADHD may have difficulty following directions, remembering information, concentrating, organizing tasks or completing work within time limits. If these difficulties are not managed appropriately, they can cause associated behavioral, emotional, social, vocational and academic problems.

Adult ADHD Stats

ADHD afflicts approximately 3% to 5% of school-age children and an es...

Read the Adult ADHD (Attention Deficit Hyperactivity Disorder) article »

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Intuniv

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INTUNIV®
(guanfacine) Extended-Release Tablets

DRUG DESCRIPTION

INTUNIV® is a once-daily, extended-release formulation of guanfacine hydrochloride (HCl) in a matrix tablet formulation for oral administration only. The chemical designation is N-amidino-2-(2,6-dichlorophenyl) acetamide monohydrochloride. The molecular formula is C₉H₉Cl₂ N₃O·HCl corresponding to a molecular weight of 282.55. The chemical structure is:

INTUNIV® (guanfacine) Structural Formula Illustration

Guanfacine HCl is a white to off-white crystalline powder, sparingly soluble in water (approximately 1 mg/mL) and alcohol and slightly soluble in acetone. The only organic solvent in which it has relatively high solubility is methanol ( > 30 mg/mL). Each tablet contains guanfacine HCl equivalent to 1 mg, 2 mg, 3 mg, or 4 mg of guanfacine base. The tablets also contain hypromellose, methacrylic acid copolymer, lactose, povidone, crospovidone, microcrystalline cellulose, fumaric acid, and glyceryl behenate. In addition, the 3mg and 4mg tablets also contain green pigment blend PB-1763.

What are the precautions when taking guanfacine (Intuniv)?

Before taking guanfacine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: kidney disease, liver disease, fainting, blood pressure problems (both low or high), slow heart rate.

This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.

To reduce the risk of dizziness and fainting, avoid becoming dehydrated or overheated during exercise, especially...

Read All Potential Precautions of Intuniv »

Last reviewed on RxList: 6/17/2011
This monograph has been modified to include the generic and brand name in many instances.