August 29, 2016
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Inversine Patient Information Including Side Effects

Brand Names: Inversine

Generic Name: mecamylamine (Pronunciation: meck a MILL a meen)

What is mecamylamine (Inversine)?

Mecamylamine is used to treat moderate to severe hypertension (high blood pressure). Because of its many side effects, mecamylamine is not commonly used.

Mecamylamine may also be used for purposes other than those listed in this medication guide.

What are the possible side effects of mecamylamine (Inversine)?

If you experience any of the following serious side effects, stop taking mecamylamine and seek emergency medical attention:

  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); or
  • abdominal pain, abdominal distention, or diarrhea.

Other, less serious side effects may be more likely to occur. Continue to take mecamylamine and talk to your doctor if you experience

  • nausea, vomiting, or constipation;
  • dry mouth;
  • decreased appetite;
  • dizziness and fainting;
  • drowsiness or weakness;
  • dilated (large) pupils and blurred vision; or
  • difficulty urinating.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

Read the Inversine (mecamylamine) Side Effects Center for a complete guide to possible side effects

What is the most important information I should know about mecamylamine (Inversine)?

Use caution when driving, operating machinery, or performing other hazardous activities. Mecamylamine may cause dizziness. If you experience dizziness, avoid these activities.

If you experience dizziness, rise slowly from a sitting or lying position to avoid falling.

Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking mecamylamine.

Take mecamylamine every day at the same time, usually after meals.

Call your doctor if you experience tremor, abdominal pain, abdominal distention, or diarrhea.

Side Effects Centers

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


Get tips on handling your hypertension.