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Inversine Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Inversine (mecamylamine HCl) is an antihypertensive medication used to treat moderate to severe hypertension (high blood pressure). The brand name of this medication is discontinued, but generic versions may be available. Common side effects include nausea, vomiting, constipation, dry mouth, decreased appetite, dizziness and fainting, drowsiness or weakness, dilated (large) pupils and blurred vision, or difficulty urinating.
Therapy with Inversine is usually started with one 2.5 mg twice a day. The average total daily dosage of Inversine is 25 mg, usually in three divided doses. Inversine may interact with antibiotics, sulfa drugs, other drugs used to lower high blood pressure, drugs used to treat other heart conditions, or anesthesia. Tell your doctor all medications and supplements you use. It is unknown if Inversine will harm a fetus. Do not take this medication without first talking to your doctor if you are pregnant. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.
Our Inversine (mecamylamine HCl) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information in Detail?
Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.
Inversine in Detail - Patient Information: Side Effects
If you experience any of the following serious side effects, stop taking mecamylamine and seek emergency medical attention:
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); or
- abdominal pain, abdominal distention, or diarrhea.
Other, less serious side effects may be more likely to occur. Continue to take mecamylamine and talk to your doctor if you experience
- nausea, vomiting, or constipation;
- dry mouth;
- decreased appetite;
- dizziness and fainting;
- drowsiness or weakness;
- dilated (large) pupils and blurred vision; or
- difficulty urinating.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Inversine (Mecamylamine) »
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Inversine FDA Prescribing Information: Side Effects
The following adverse reactions have been reported and within each category are listed in order of decreasing severity.
Respiratory:Interstitial pulmonary edema and fibrosis.
Special Senses: Blurred vision, dilated pupils.
Miscellaneous: Weakness, fatigue, sedation.
Read the entire FDA prescribing information for Inversine (Mecamylamine) »
Additional Inversine Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Get tips on handling your hypertension.