Invirase (Saquinavir Mesylate) Drug Center: Guide to Drug Information for Professionals, Patients and Caregivers at RxList

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May 27, 2012

Invirase

HIV and AIDS: Antiretroviral Drugs, Treatments and Medications »

Entry Inhibitors (including Fusion Inhibitors) and CCR5 Co-receptor Antagonist

Entry Inhibitors
Entry inhibitors block HIV entry into CD4+ cells.

Fusion inhibitors
The only drug in this class is T-20, which is administered as a twice daily subcutaneous injection. The most common side effect is redness and pain at the site of injection. Rarely, infection can occur at the injection site. There also are reports of generalized allergic reactions.

CCR5 antagonist
Although there were some early concerns of liver inflammation for drugs in this class, MVC appeared to be well tolerated in clinical trials without any specific toxicities attributable to the drug. However, it is a new drug in a new class and the first to actually target the cell. For these reasons, longer follow-up from clinical trials and those followed in the clinic will be very important for assessing the overall safety of the...

Read the HIV and AIDS: Antiretroviral Drugs, Treatments and Medications article »

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Invirase

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Invirase Drug Center

What is Prescribing information?

The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.

Invirase Prescribing Information: Indications & Dosage

INVIRASE® (saquinavir mesylate) Structural Formula Illustration

INVIRASE in combination with ritonavir and other antiretroviral agents is indicated for the treatment of HIV-1 infection in adults (over the age of 16 years).

The following points should be considered when initiating therapy with INVIRASE:

The twice daily administration of INVIRASE in combination with ritonavir is supported by safety data from the MaxCmin 1 study [see ADVERSE REACTIONS] and pharmacokinetic data [see CLINICAL PHARMACOLOGY].
The efficacy of INVIRASE with ritonavir has not been compared against the efficac...

Read the complete drug monograph for Invirase »

What is Invirase Prescribing Information?

Drug Description - Indications & Dosage - Side Effects & Drug Interactions - Warnings & Precautions - Contraindications - Medication Guide and More

What is Patient information?

Easy-to-read and understand detailed drug information and pill images for the patient or caregiver from Cerner Multum.

Invirase Patient Information: Side Effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop taking saquinavir and call your doctor at once if you have any of these serious side effects:

fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;
increased urination or extreme thirst;
easy bruising or bleeding;
signs of a new infection, such as fever or chills, cough, or flu symptoms; or
nausea, stomach pain, low fever, l...

Read the complete patient information for Invirase »

What is Invirase Patient Information?

Possible Side Effects - Images - What Is - How Should I Take It - What If I Miss a Dose - What Should I Avoid and More

What is Consumer information?

A concise overview of the drug for the patient or caregiver from First DataBank.

Invirase Consumer Information: Uses

Saquinavir, used in combination with ritonavir and other medications, is used to help treat your HIV infection, thereby improving your quality of life. It also lowers your risk of getting HIV complications (such as new infections, cancer). Saquinavir belongs to a class of drugs known as protease inhibitors.

Saquinavir is not a cure for HIV. It does not prevent the spread of HIV to others through sexual contact or blood contamination (such as sharing used needles).

HOW TO USE: Read the Medication Guide provided by your pharmacist before you start ...

Read the complete consumer information for Invirase »