Recommended Topic Related To:


"The U.S. Food and Drug Administration is alerting hospitals, health care professionals, and patients of a voluntary recall of all non-expired drug products produced and distributed for sterile use by Abrams Royal Compounding Pharmacy in Dallas, T"...




There were no instances of overdosage with IPLEX (mecasermin rinfabate [rdna origin] injection) in the Primary IGFD clinical trial. Based on the known pharmacological effects of IGF-1, acute overdosage could lead to hypoglycemia. Treatment of acute overdosage of IPLEX (mecasermin rinfabate [rdna origin] injection) should be directed at reversing hypoglycemia. Mild hypoglycemia can usually be treated with oral glucose or food. If the overdose results in loss of consciousness, treatment with parenteral glucagon or intravenous glucose may be required.

Long-term overdosage could result in signs and/or symptoms of acromegaly.


IPLEX (mecasermin rinfabate [rDNA origin] injection) should not be used for growth promotion in patients with closed epiphyses.

IPLEX (mecasermin rinfabate [rdna origin] injection) is contraindicated in the presence of active or suspected neoplasia, and therapy should be discontinued when there is any evidence of active neoplasia.

IPLEX (mecasermin rinfabate [rdna origin] injection) is contraindicated in patients allergic to mecasermin rinfabate (rhIGF-1/rhIGFBP-3) or any of the excipients in IPLEX (mecasermin rinfabate [rdna origin] injection) .

Intravenous administration of IPLEX (mecasermin rinfabate [rdna origin] injection) is contraindicated.

Last reviewed on RxList: 3/2/2009
This monograph has been modified to include the generic and brand name in many instances.


Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Women's Health

Find out what women really need.

Related Drugs
Use Pill Finder Find it Now See Interactions

Pill Identifier on RxList

  • quick, easy,
    pill identification

Find a Local Pharmacy

  • including 24 hour, pharmacies

Interaction Checker

  • Check potential drug interactions
Search the Medical Dictionary for Health Definitions & Medical Abbreviations