"Potential drug treatments are tested on paper, in laboratories and eventually in thousands of people. But every drug that goes through this cycle â€“ every drug that FDA approves â€“ carries some risk. One of the first lines of defense against "...
- Clinician Information:
Iplex Patient Information including How Should I Take
In this Article
- What is mecasermin rinfabate (Iplex)?
- What are the possible side effects of mecasermin rinfabate (Iplex)?
- What is the most important information I should know about mecasermin rinfabate (Iplex)?
- What should I discuss with my healthcare provider before using mecasermin rinfabate (Iplex)?
- How should I use mecasermin rinfabate (Iplex)?
- What happens if I miss a dose (Iplex)?
- What happens if I overdose (Iplex)?
- What should I avoid while using mecasermin rinfabate (Iplex)?
- What other drugs will affect mecasermin rinfabate (Iplex)?
- Where can I get more information?
What should I discuss with my healthcare provider before using mecasermin rinfabate (Iplex)?
Your child should not use mecasermin rinfabate if the child:
- has finished growing (the bone growth plates are closed);
- has cancer; or
- has other causes of growth failure.
Before receiving this medication, tell your child's doctor if the child has:
- kidney problems;
- liver problems; or
- scoliosis (a curved spine).
If your child has any of these conditions, he or she may need a dose adjustment or special tests to safely use mecasermin rinfabate.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether mecasermin rinfabate passes into breast milk or if it could harm a nursing baby. This medication should not be used while breast-feeding a baby.
How should I use mecasermin rinfabate (Iplex)?
Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your child's prescription label.
Your child's doctor may occasionally change the dose to make sure your child gets the best results from this medication.
Mecasermin rinfabate is given as an injection (shot) under the skin in your child's upper arm, upper thigh, stomach area, or buttocks. Never inject the medicine into a muscle or a vein. Your doctor, nurse, or pharmacist will give you specific instructions on how and where to inject this medicine. Do not inject your child at home if you do not fully understand how to give the injection and properly dispose of used needles and syringes.
Use a different place in the injection skin area each time you give an injection. Your care provider will show you the places on your child's body where you can safely inject the medication. Do not inject into the same place two times in a row.
This medicine must be given 20 minutes before or after the child eats a meal or snack. Do not use the medicine if the meal or snack is not eaten for any reason. Wait until the child has eaten and 20 minutes have passed before giving the mecasermin rinfabate injection.
Do not draw the mecasermin rinfabate dose into a syringe until you are ready to give your child an injection. Do not use the medication if it has changed colors or has any particles in it. Call your doctor for a new prescription.
Use each disposable needle only one time. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.
Your child may need to eat or restrict certain foods while using this medication. Follow the doctor's instructions about diet and medication.
To be sure this medication is helping your child's condition, the child's blood will need to be tested on a regular basis. An eye exam may also be needed. Do not miss any scheduled appointments.
Store this medication in the freezer until you are ready to use it. It is best to keep the medicine in a deep freezer at a temperature of 4 degrees below 0 Fahrenheit (or -20 degrees Celsius) so it does not thaw between uses.
When you are ready to use the medication, take it out of the freezer and allow it to thaw at room temperature for 45 minutes. Do not warm the medication with hot water or a microwave. Once the medicine thaws, it must be used within 1 hour.
Mecasermin rinfabate can be stored frozen for up to 2 months. Do not use the medication if it has been frozen for longer than 2 months.
Additional Iplex Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Find out what women really need.