IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

GEFITINIB - ORAL

(ge-FI-ti-nib)

COMMON BRAND NAME(S): Iressa

WARNING: Gefitinib has rarely caused very serious (possibly fatal) liver disease. Tell your doctor immediately if you develop symptoms of liver disease, including stomach/abdominal pain, extreme fatigue, dark urine, yellowing eyes/skin.

USES: Gefitinib is used to treat lung cancer. It works by slowing or stopping the growth of cancer cells. Gefitinib blocks a certain protein (an enzyme called tyrosine kinase).

HOW TO USE: Take gefitinib by mouth once daily, with or without food, or as directed.

Medications which reduce or completely block stomach acid (e.g., proton pump inhibitors/PPIs, H2 blockers, antacids) may decrease the absorption of gefitinib. This could decrease the effectiveness of gefitinib. Consult your doctor or pharmacist if you are taking any of these medications.

Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may. Grapefruit may increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details.

Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time each day.