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Irritable Bowel Syndrome (IBS) (cont.)

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What is the treatment for irritable bowel syndrome?

Dietary modifications are the first treatments that should be tried to treat IBS. There are several types of foods in particular that often trigger characteristic symptoms and signs.

If dietary modifications and lifestyle changes do not adequately treat the symptoms and signs, a doctor may recommend medical therapies.

What medications treat diarrhea (IBS-D) and constipation (IBS-D) in irritable bowel syndrome?

Medicine for diarrhea

  • Antidiarrheal medications such as loperamide (Imodium), attapulgite (Kaopectate), and diphenoxylate and atropine (Lomotil) can be helpful if loose stools are one of the main signs. Eluxadoline (Viberzi) is a prescription for the treatment of irritable bowel syndrome with diarrhea (IBS-D).
  • For females with IBS who experience severe diarrhea, alosetron (Lotronex) has been used.
  • Rifaximin (Xifaxan) is an antibiotic for the treatment of irritable bowel syndrome with diarrhea (IBS-D) and IBS-related bloating.
  • Bile acid binders including cholestyramine ( (Prevalite), colestipol (Colestid), or colesevelam (Welchol) can help some patients with IBS-D, but can also cause bloating.

Medicine for constipation medication

  • Over-the-counter laxatives such as polyethylene glycol 3350 ( (MiraLax), bisacodyl (Dulcolax), and psyllium seed husks (Metamucil) can help relieve constipation and keep bowel movements regular. Senna laxatives (Senokot, Ex-Lax Gentle Nature) may be taken short-term. Prescription laxatives such as lactulose (Constulose) may also be prescribed.
  • Two drugs specifically used to treat IBS are lubiprostone (Amitiza), a laxative, and linaclotide (Linzess), a constipation medication.
  • SSRI antidepressants fluoxetine (Prozac), citalopram (Celexa), sertraline (Zoloft), paroxetine (Paxil), and escitalopram (Lexapro) may be helpful for those with constipation (IBS-C), but they can trigger IBS attacks in patients with diarrhea (IBS-D).

What medications treat pain and cramping in irritable bowel syndrome (IBS)?

  • Antispasmodics, such as metoclopramide (Reglan), dicyclomine (Bentyl), and hyoscyamine (Levsin), decrease symptoms of pain and cramping.
  • Antidepressants such as amitriptyline (Elavil, Paregoric), doxepin ( (Silenor), desipramine (Norpramin), nortriptyline (Pamelor), and imipramine (Tofranil) may help with abdominal pain but due to side effects are usually reserved for severe cases.

What other medication may help signs and symptoms of irritable bowel syndrome (IBS)?

  • Antidepressants in low doses, such as tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs), may help relieve symptoms associated with IBS.
  • Bismuth subsalicylate (Pepto-Bismol) and magnesium hydroxide (Milk of Magnesia).
  • Antibiotics may be used when small intestinal bacterial overgrowth (SIBO) is suspected.
  • Antianxiety medications such as diazepam (Valium), lorazepam (Ativan), and clonazepam (Klonopin) are occasionally prescribed short-term for people whose anxiety worsens their irritable bowel syndrome symptoms.
Medically Reviewed by a Doctor on 1/27/2017

Source: MedicineNet.com
http://www.medicinenet.com/irritable_bowel_syndrome_ibs/article.htm

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