"Nov. 1, 2012 -- Having even mildly elevated blood pressure at midlife prematurely ages the brain, a new study shows.
Researchers say the early changes seen with higher blood pressure may set the stage for problems with thinking, memor"...
(Generic versions may still be available.)
The following adverse reactions have been observed but there are not enough data to support an estimate of their frequency. Consequently the reactions are categorized by organ system and are listed in decreasing order of severity and not frequency.
Neurologic: Syncope resulting from either postural or exertional hypotension; dizziness; blurred vision; muscle tremor; ptosis of the lids; mental depression; chest paresthesias; weakness; lassitude; fatigue.
Metabolic: Weight gain
Read the Ismelin (guanethidine monosulfate) Side Effects Center for a complete guide to possible side effects
Concurrent use of Ismelin (guanethidine monosulfate) and rauwolfia derivatives may cause excessive postural hypotension, bradycardia, and mental depression.
Both digitalis and Ismelin (guanethidine monosulfate) slow the heart rate.
Amphetamine-like compounds, stimulants (e.g., ephedrine, methylphenidate), tricyclic antidepressants (e.g., amitriptyline, imipramine, desipramine) and other psychopharmacologic agents (e.g., phenothiazines and related compounds), as well as oral contraceptives, may reduce the hypotensive effect of Ismelin (guanethidine monosulfate) .
MAO inhibitors should be discontinued for at least 1 week before starting therapy with Ismelin (guanethidine monosulfate) . This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 12/8/2004
Additional Ismelin Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Get tips on handling your hypertension.