Brand Names: Imdur, ISMO, Monoket

Generic Name: isosorbide mononitrate (Pronunciation: EYE soe SOR bide MON oh NYE trate)

• What is isosorbide mononitrate (Ismo)?
• What are the possible side effects of isosorbide mononitrate (Ismo)?
• What is the most important information I should know about isosorbide mononitrate (Ismo)?
• What should I discuss with my healthcare provider before taking isosorbide mononitrate (Ismo)?
• How should I take isosorbide mononitrate (Ismo)?
• What happens if I miss a dose (Ismo)?
• What happens if I overdose (Ismo)?
• What should I avoid while taking isosorbide mononitrate (Ismo)?
• What other drugs will affect isosorbide mononitrate (Ismo)?
• Where can I get more information?

What is isosorbide mononitrate (Ismo)?

Isosorbide mononitrate is in a group of drugs called nitrates. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.

Isosorbide mononitrate is used to prevent angina attacks (chest pain).

Isosorbide mononitrate will not treat an angina attack that has already begun.

Isosorbide mononitrate may also be used for other purposes not listed in this medication guide.

Imdur 120 mg

oblong, white, imprinted with IMDUR, 120

Imdur 30 mg

oblong, pink, imprinted with IM DUR, 30 30

Imdur 60 mg

elliptical, yellow, imprinted with IM DUR, 60 60

Isosorbide Mononitrate 10 mg-PUR

round, blue, imprinted with R631

Isosorbide Mononitrate 20 mg-KU

round, white, imprinted with 20, KU 107

Isosorbide Mononitrate 20 mg-TEV

round, yellow, imprinted with 93 76

Isosorbide Mononitrate 30 mg-ETH

oval, red, imprinted with E 30

Isosorbide Mononitrate 60 mg-ETH

oval, yellow, imprinted with E 60

Isosorbide Mononitrate ER 120 mg-ETH

oval, white, imprinted with E 120

Isosorbide SR 30 mg-WAR

elliptical, pink, imprinted with A 11

Monoket 10 mg

round, white, imprinted with 10, Schwarz 610

Monoket 20 mg

round, white, imprinted with 20, SCHWARZ 620

What are the possible side effects of isosorbide mononitrate (Ismo)?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

• fast, slow, pounding, or uneven heart rate;
• feeling like you might pass out;
• trouble breathing, blue-colored skin, tired feeling; or
• worsening angina pain.

Less serious side effects may include:

• headache, mild dizziness;
• warmth, redness, or tingling under your skin;
• nausea, vomiting, constipation, diarrhea;
• pain or stiffness in joints or muscles;
• hot flashes; or
• dry mouth.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about isosorbide mononitrate (Ismo)?

Do not use isosorbide mononitrate if you are taking sildenafil (Viagra). Serious, life-threatening side effects can occur if you take isosorbide mononitrate while you are using sildenafil.

You should not use this medication if you are allergic to isosorbide mononitrate, isosorbide dinitrate, (Isordil, Dilatrate, Isochron), or nitroglycerin, or if you have early signs of a heart attack (chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling).

Before taking isosorbide mononitrate, tell your doctor if you have congestive heart failure, low blood pressure, or kidney disease.

Isosorbide mononitrate can cause severe headaches, especially when you first start using it. These headaches may gradually become less severe as you continue to use the medication. Do not stop taking isosorbide mononitrate. Ask your doctor before using any headache pain medication.

Isosorbide mononitrate will not treat an angina attack that has already begun.

It is important to keep taking this medicine as directed to prevent an angina attack. Get your prescription refilled before you run out of medicine completely.

Do not stop taking isosorbide mononitrate suddenly. Stopping suddenly could cause a severe angina attack.