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Isopto Carpine

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Isopto Carpine

Isopto® Carpine
(pilocarpine hydrochloride) Ophthalmic Solution 1%, 2% and 4%

Isopto Carpine

DRUG DESCRIPTION

Isopto® Carpine (pilocarpine hydrochloride ophthalmic solution) is a cholinergic agonist prepared as a sterile topical ophthalmic solution. The active ingredient is represented by the chemical structure:

Isopto® Carpine
(pilocarpine hydrochloride) Structural Formula Illustration

Established name: pilocarpine hydrochloride Chemical name: 2(3H)-furanone, 3­ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)­methyl]-monohydrochloride, (3S-cis)-.

Molecular Formula: C11H16N2O2 •HCl

Molecular Weight: 244.72

Each mL of Isopto Carpine (pilocarpine hydrochloride ophthalmic solution) contains: Active: pilocarpine hydrochloride 1% (10 mg/mL), 2% (20 mg/mL), or 4% (40 mg/mL). Preservative: benzalkonium chloride 0.01%. Inactives: hypromellose 2910, boric acid, sodium citrate, sodium chloride (present in 1% only); hydrochloric acid and/or sodium hydroxide (to adjust pH); purified water. Isopto® Carpine (pilocarpine) has a pH of 3.5 to 5.5 and an osmolality of 290 to 350 mOsm/kg (1% and 2% products) and 550 to 600 mOsm/kg (4% product).

What are the precautions when taking pilocarpine (Isopto Carpine)?

Before using pilocarpine, tell your doctor or pharmacist if you are allergic to it; or to preservatives (e.g., benzalkonium chloride); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: asthma, other eye problems (e.g., iritis, detached retina), heart disease (e.g., heart failure, recent heart attack), low or high blood pressure, overactive thyroid (hyperthyroidism), Parkinsonism, stomach/intestinal problems (e.g., ulcers, spasms).

After you apply pilocarpine, your vision may become temporarily blurred or unstable. Vision in dim light may be affected....

Read All Potential Precautions of Isopto Carpine »

Last reviewed on RxList: 7/21/2010
This monograph has been modified to include the generic and brand name in many instances.

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Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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