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Isopto Carpine Side Effects Center
Medical Editor: John P. Cunha, DO, FACOEP
Isopto Carpine (pilocarpine hydrochloride) Ophthalmic Solution is used alone or with other medications to treat high pressure inside the eye due to glaucoma or other eye diseases (e.g., ocular hypertension). It may also be used during certain eye surgeries and to reverse the effects of drugs used to enlarge the pupil (e.g., during an eye exam). It is a cholinergic agonist. Common side effects include temporary irritation/burning/stinging of the eye, temporary blurred vision, poor vision in dim light, headache, or brow ache.
The usual dose of Isopto Carpine 1%, 2% or 4% is one drop applied topically in the eye(s) up to four times daily. Isopto Carpine may interact with other eye medications. Tell your doctor all medications and supplements you use. During pregnancy, Isopto Carpine should be used only when prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.
Our Isopto Carpine (pilocarpine hydrochloride) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is Patient Information Overview?
A concise overview of the drug for the patient or caregiver from First DataBank.
Isopto Carpine Overview - Patient Information: Side Effects
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: eye pain, flushing, diarrhea, nausea, stomach/abdominal pain or cramps, increased saliva, unusual sweating, vision changes.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Isopto Carpine (Pilocarpine)
What is Prescribing information?
The FDA package insert formatted in easy-to-find categories for health professionals and clinicians.
Isopto Carpine FDA Prescribing Information: Side Effects
Clinical Studies Experience
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.
The safety data described below reflect exposure in four controlled clinical trials of 90 days to 2 years duration in 317 patients diagnosed with open-angle glaucoma or ocular hypkertension. In the four clinical trials, patients were treated with Isopto® Carpine 2%, two to four times daily or with pilocarpine 1%, 1.75% or 2% in fixed combination with betaxolol 0.25%, two or three times daily.
The most frequently reported adverse reactions occurring in ≥ 5 % of patients in the pilocarpine 2% populations were: headache/browache, accommodative change, blurred vision, eye irritation, visual impairment (dim, dark, or “jumping” vision), and eye pain.
The adverse reaction profile reported for the use of Isopto® Carpine (pilocarpine) in pediatric patients is comparable to that seen in adult patients.
Read the entire FDA prescribing information for Isopto Carpine (Pilocarpine)
Additional Isopto Carpine Information
- Isopto Carpine Drug Interactions Center: pilocarpine hcl opht
- Isopto Carpine Side Effects Center
- Isopto Carpine Overview including Precautions
- Isopto Carpine FDA Approved Prescribing Information including Dosage
Isopto Carpine - User Reviews
Isopto Carpine User Reviews
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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