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Isopto Hyoscine

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Isopto Hyoscine

Discontinued Warning IconPlease Note: This Brand Name drug is no longer available in the US.
(Generic versions may still be available.)

Isopto Hyoscine
(scopolamine hydrobromide)


ISOPTO® HYOSCINE (Scopolamine Hydrobromide) is an anticholinergic prepared as a sterile topical ophthalmic solution.


Established name: Scopolamine Hydrobromide

Chemical name: Benzeneacetic acid , a-(hydroxymethyl)- , 9-methyl-3-oxa-9azatricyclo[3 .3. 1 .O2 -4]non-7-yl ester, hydrobromide, trihydrate, [7(S)-(1 a,2b,4b,5a,7b)]-.

Each ml contains:

    Active: Scopolamine Hydrobromide 0.25%.
    Preservative: Benzalkonium Chloride 0.01%.
    Vehicle: Hydroxypropyl Methylcellulose 0.5%.
    Inactive: Sodium Chloride, Glacial Acetic Acid, Sodium Acetate (to adjust pH), Purified Water.

What are the possible side effects of scopolamine ophthalmic (Isopto Hyoscine)?

If you experience any of the following serious side effects, stop using scopolamine ophthalmic and seek emergency medical attention:

  • an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
  • an irregular or fast heart rate;
  • hallucinations or unusual behavior (especially in children); or
  • a swollen or distended stomach (in infants).

Other, less serious side effects may be more likely to occur. Continue to use scopolamine ophthalmic and talk to your doctor if you...

Read All Potential Side Effects and See Pictures of Isopto Hyoscine »

What are the precautions when taking scopolamine (Isopto Hyoscine)?

Before using scopolamine, tell your doctor or pharmacist if you are allergic to it; or to atropine, other belladonna-type drugs; or if you have any other allergies. This product may contain inactive ingredients (such as preservatives like benzalkonium chloride), which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: personal or family history of glaucoma (angle-closure type), brain damage or spastic paralysis in children, Down's syndrome, certain eye conditions (e.g., thinning cornea also known as keratoconus, or scarring between the cornea, iris, and lens).

This drug may cause blurred vision. Your eyes may also become sensitive to...

Read All Potential Precautions of Isopto Hyoscine »

Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.

Isopto Hyoscine - User Reviews

Isopto Hyoscine User Reviews

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Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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