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Istalol® (timolol maleate) ophthalmic solution 0.5% is a non-selective beta-adrenergic receptor blocking agent indicated in the treatment of elevated intraocular pressure (IOP) in patients with ocular hypertension or open-angle glaucoma.


One drop of Istalol® (timolol maleate ophthalmic solution) 0.5% should be administered in the affected eye(s) once a day in the AM.


Dosage Forms And Strengths

Topical ophthalmic solution containing 5 mg/mL timolol (6.8 mg/mL of timolol maleate).

Storage And Handling

Istalol® (timolol maleate ophthalmic solution) 0.5% is supplied in white LDPE bottles with 15 mm LDPE yellow caps and 15 mm LDPE white dropper tips as follows:

5 mL in 10mL container (NDC 67425-003-50)
2.5 mL in 7.5mL container (NDC 67425-003-12)


Store at 15° – 25°C (59° – 77°F).

Manufactured for: SENJU Pharmaceutical Co., Ltd Osaka, Japan 541-0046. By: Bausch & Lomb Incorporated. Distributed by: ISTA Pharmaceuticals®, Inc. Tampa, FL 33637, Irvine, CA 92618. Revised: 6/2013

Last reviewed on RxList: 7/1/2013
This monograph has been modified to include the generic and brand name in many instances.


Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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