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Istalol

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Istalol

Overdosage
Contraindications

OVERDOSE

There have been reports of inadvertent overdosage with Istalol® resulting in systemic effects similar to those seen with systemic beta-adrenergic blocking agents such as dizziness, headache, shortness of breath, bradycardia, bronchospasm, and cardiac arrest. An in vitro hemodialysis study, using 14C timolol added to human plasma or whole blood, showed that timolol was readily dialyzed from these fluids; however, a study of patients with renal failure showed that timolol did not dialyze readily.

CONTRAINDICATIONS

Asthma, COPD

Istalol® is contraindicated in patients with bronchial asthma; a history of bronchial asthma; severe chronic obstructive pulmonary disease (see WARNINGS AND PRECAUTIONS).

Sinus Bradycardia, AV Block, Cardiac Failure, Cardiogenic Shock

Istalol® is contraindicated in patients with sinus bradycardia; second or third degree atrioventricular block; overt cardiac failure (see WARNINGS AND PRECAUTIONS); cardiogenic shock.

Hypersensitivity Reactions

Istalol® is contraindicated in patients who have exhibited a hypersensitivity reaction to any component of this product in the past.

Last reviewed on RxList: 7/1/2013
This monograph has been modified to include the generic and brand name in many instances.

Overdosage
Contraindications
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