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(isoproterenol hydrochloride) Sterile Injection, USP


Isoproterenol hydrochloride is 3,4-Dihydroxy-α-[(isopropylamino)methyl] benzyl alcohol hydrochloride, a synthetic sympathomimetic amine that is structurally related to epinephrine but acts almost exclusively on beta receptors. The molecular formula is C11H17NO3 • HCl. It has a molecular weight of 247.72 and the following structural formula:

Isoproterenol hydrochloride is a racemic compound.

Isuprel™ (Isoproterenol Hcl) Structural Formula Illustration

Each milliliter of the sterile solution contains:

Isoproterenol hydrochloride injection, USP ------------0.2 mg
Edetate Disodium (EDTA) -------------------------------0.2 mg
Sodium Chloride ---------------------------------------7.0 mg
Sodium Citrate, Dihydrate -----------------------------2.07 mg
Citric Acid, Anhydrous --------------------------------2.5 mg
Water for Injection -----------------------------------1.0 mL

The pH is adjusted between 2.5 and 4.5 with hydrochloric acid or sodium hydroxide.

The sterile solution is nonpyrogenic and can be administered by the intravenous, intramuscular, subcutaneous, or intracardiac routes.

What are the possible side effects of isoproterenol inhalation (Isuprel Mistometer)?

If you experience any of the following serious side effects, stop using isoproterenol inhalation and seek emergency medical attention or contact your doctor immediately:

  • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or
  • chest pain or an irregular heartbeat.

Other, less serious side effects may be more likely to occur. Continue to use isoproterenol inhalation and talk to your doctor if you experience

  • headache, dizziness, lightheadedness, or...

Read All Potential Side Effects and See Pictures of Isuprel »

Last reviewed on RxList: 4/8/2013
This monograph has been modified to include the generic and brand name in many instances.

Report Problems to the Food and Drug Administration


You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

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