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ISUPREL®
Isoproterenol Hydrochloride Injection, USP
Sterile Injection 1:5000
Isoproterenol hydrochloride is 3,4-Dihydroxy-a-[(isopropylamino) methyl] benzyl alcohol hydrochloride, a synthetic sympathomimetic amine that is structurally related to epinephrine but acts almost exclusively on beta receptors. The molecular formula is C11H17NO3 · HCl. It has a molecular weight of 247.72 and the following structural formula:
Isoproterenol hydrochloride is a racemic compound.
Each milliliter of the sterile 1:5000 solution contains: (isoproterenol)
| ISUPREL, brand of isoproterenol hydrochloride injection, USP | 0.2 mg |
| Lactic Acid | 0.12mg |
| Sodium Chloride | 7.0 mg |
| Sodium Lactate | 1.8mg |
| Sodium Metabisulfite (as preservative) | 1.0 mg |
| Water for Injection qs ad | 1.0 mL |
The pH is adjusted between 2.5 and 4.5 with hydrochloric acid. The air in the ampuls has been displaced by nitrogen gas.
The sterile 1:5000 solution is nonpyrogenic and can be administered by the intravenous, intramuscular, subcutaneous, or intracardiac routes.
If you experience any of the following serious side effects, stop using isoproterenol inhalation and seek emergency medical attention or contact your doctor immediately:
Other, less serious side effects may be more likely to occur. Continue to use isoproterenol inhalation and talk to your doctor if you experience
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Last reviewed on RxList: 12/8/2004
This monograph has been modified to include the generic and brand name in many instances.
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