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Isuprel

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Isuprel

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Isuprel™
(isoproterenol hydrochloride) Sterile Injection, USP

DRUG DESCRIPTION

Isoproterenol hydrochloride is 3,4-Dihydroxy-α-[(isopropylamino)methyl] benzyl alcohol hydrochloride, a synthetic sympathomimetic amine that is structurally related to epinephrine but acts almost exclusively on beta receptors. The molecular formula is C11H17NO3 • HCl. It has a molecular weight of 247.72 and the following structural formula:

Isoproterenol hydrochloride is a racemic compound.

Isuprel™ (Isoproterenol Hcl) Structural Formula Illustration

Each milliliter of the sterile solution contains:

Isoproterenol hydrochloride injection, USP ------------0.2 mg
Edetate Disodium (EDTA) -------------------------------0.2 mg
Sodium Chloride ---------------------------------------7.0 mg
Sodium Citrate, Dihydrate -----------------------------2.07 mg
Citric Acid, Anhydrous --------------------------------2.5 mg
Water for Injection -----------------------------------1.0 mL

The pH is adjusted between 2.5 and 4.5 with hydrochloric acid or sodium hydroxide.

The sterile solution is nonpyrogenic and can be administered by the intravenous, intramuscular, subcutaneous, or intracardiac routes.

Last reviewed on RxList: 4/8/2013
This monograph has been modified to include the generic and brand name in many instances.

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