"The US Food and Drug Administration (FDA) has received multiple adverse event reports associated with the use of the Vascu-Guard Peripheral Vascular Patch (Baxter International Inc) during carotid endarterectomy (CEA).
The following reactions to isoproterenol hydrochloride injection have been reported:
CNS: Nervousness, headache, dizziness, nausea, visual blurring.
In a few patients, presumably with organic disease of the AV node and its branches, isoproterenol hydrochloride injection has been reported to precipitate Adams-Stokes seizures during normal sinus rhythm or transient heart block.
Other: Flushing of the skin, sweating, mild tremors, weakness, pallor.
Read the Isuprel (isoproterenol) Side Effects Center for a complete guide to possible side effects
Isoproterenol hydrochloride injection and epinephrine should not be administered simultaneously because both drugs are direct cardiac stimulants and their combined effects may induce serious arrhythmias. The drugs may, however, be administered alternately provided a proper interval has elapsed between doses.
Avoid ISUPREL when potent inhalational anesthetics such as halothane are employed because of potential to sensitize the myocardium to effects of sympathomimetic amines.
Read the Isuprel Drug Interactions Center for a complete guide to possible interactions
Last reviewed on RxList: 1/31/2017
Additional Isuprel Information
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Get the latest treatment options.