"The U.S. Food and Drug Administration today approved three new related products for use with diet and exercise to improve blood sugar control in adults with type 2 diabetes: Nesina (alogliptin) tablets, Kazano (alogliptin and metformin hydrochlor"...
Janumet Patient Information including If I Miss a Dose
In this Article
- What is metformin and sitagliptin (Janumet)?
- What are the possible side effects of metformin and sitagliptin (Janumet)?
- What is the most important information I should know about metformin and sitagliptin (Janumet)?
- What should I discuss with my health care provider before taking metformin and sitagliptin (Janumet)?
- How should I take metformin and sitagliptin (Janumet)?
- What happens if I miss a dose (Janumet)?
- What happens if I overdose (Janumet)?
- What should I avoid while taking metformin and sitagliptin (Janumet)?
- What other drugs will affect metformin and sitagliptin (Janumet)?
- Where can I get more information?
What happens if I miss a dose (Janumet)?
Take the missed dose as soon as you remember (be sure to take the medicine with food). Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Janumet)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. You may have signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).
An overdose of metformin may cause lactic acidosis. Get emergency medical help if you have: weakness, increasing sleepiness, slow heart rate, cold feeling, muscle pain, shortness of breath, stomach pain, feeling light-headed, and fainting.
What should I avoid while taking metformin and sitagliptin (Janumet)?
Avoid drinking alcohol. It lowers blood sugar and may increase your risk of lactic acidosis.
What other drugs will affect metformin and sitagliptin (Janumet)?
Tell your doctor about all other medicines you use, especially:
- acetazolamide (Diamox);
- cimetidine (Tagamet), ranitidine (Zantac);
- morphine (MS Contin, Kadian, Oramorph);
- ranitidine (Zantac);
- topiramate (Topamax);
- trimethoprim (Proloprim, Primsol, Bactrim, Cotrim, Septra) or vancomycin (Vancocin, Lyphocin);
- glipizide (Glucotrol, Metaglip), glimepiride (Amaryl, Avandaryl, Duetact), glyburide (DiaBeta, Micronase, Glucovance); or
- heart or blood pressure medications such as amiloride (Midamor), digoxin (Lanoxin), furosemide (Lasix), nifedipine (Nifedical, Procardia), procainamide (Procan, Pronestyl, Procanbid), quinidine (Quin-G), triamterene (Dyrenium).
You may be more likely to have hyperglycemia (high blood sugar) if you take metformin and sitagliptin with other drugs that can raise blood sugar, such as:
- diuretics (water pills);
- steroids (prednisone and others);
- heart or blood pressure medication (Cartia, Cardizem, Covera, Isoptin, Verelan, and others);
- niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others);
- phenothiazines (Compazine and others);
- thyroid medicine (Synthroid and others);
- birth control pills and other hormones;
- seizure medicines (Dilantin and others); or
- diet pills or medicines to treat asthma, colds or allergies.
These lists are not complete and there are many other medicines that can increase or decrease the effects of metformin and sitagliptin on lowering your blood sugar. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about metformin and sitagliptin.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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