"The U.S. Food and Drug Administration (FDA) is warning that the type 2 diabetes medicines canagliflozin, dapagliflozin, and empagliflozin may lead to ketoacidosis, a serious condition where the body produces high levels of blood acids called keto"...
Janumet Patient Information including How Should I Take
In this Article
- What is metformin and sitagliptin (Janumet)?
- What are the possible side effects of metformin and sitagliptin (Janumet)?
- What is the most important information I should know about metformin and sitagliptin (Janumet)?
- What should I discuss with my health care provider before taking metformin and sitagliptin (Janumet)?
- How should I take metformin and sitagliptin (Janumet)?
- What happens if I miss a dose (Janumet)?
- What happens if I overdose (Janumet)?
- What should I avoid while taking metformin and sitagliptin (Janumet)?
- What other drugs will affect metformin and sitagliptin (Janumet)?
- Where can I get more information?
What should I discuss with my health care provider before taking metformin and sitagliptin (Janumet)?
Some people develop a life-threatening condition called lactic acidosis while taking metformin. You may be more likely to develop lactic acidosis if you have liver or kidney disease, congestive heart failure, a severe infection, if you are dehydrated, or if you drink large amounts of alcohol. Talk with your doctor about your individual risk.
You should not use this medication if you are allergic to metformin (Actoplus Met, Avandamet, Fortamet, Glucophage, Riomet) or sitagliptin (Januvia), or if you have:
- kidney or liver disease; or
- if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).
To make sure you can safely take this medication, tell your doctor if you have a history of heart disease or pancreatitis, or if you are over 80 years old and have not recently had your kidney function checked.
If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you will need to temporarily stop taking metformin and sitagliptin. Be sure your caregivers know ahead of time that you are using this medication.
Certain oral diabetes medications may increase your risk of serious heart problems. However, not treating your diabetes can damage your heart and other organs.
FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether metformin and sitagliptin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
How should I take metformin and sitagliptin (Janumet)?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office.
Take metformin and sitagliptin with meals.
Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time.
Know the signs of low blood sugar (hypoglycemia) and how to recognize them: headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating.
Check your blood sugar carefully during a time of stress or illness, if you travel, exercise more than usual, drink alcohol, or skip meals. These things can affect your glucose levels and your dose needs may also change.
Always keep a source of sugar available in case you have symptoms of low blood sugar. Sugar sources include orange juice, glucose gel, candy, or milk. If you have severe hypoglycemia and cannot eat or drink, use an injection of glucagon. Your doctor can give you a prescription for a glucagon emergency injection kit and tell you how to give the injection.
Ask your doctor how to adjust your metformin and sitagliptin dose if needed. Do not change your medication dose or schedule without your doctor's advice.
Metformin and sitagliptin is only part of a complete program of treatment that may also include diet, exercise, weight control, foot care, and eye care. Follow your diet, medication, and exercise routines very closely.
Store at room temperature away from moisture and heat.
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