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Janumet Patient Information Including Side Effects
Brand Names: Janumet, Janumet XR
Generic Name: metformin and sitagliptin (Pronunciation: met FOR min and SI ta glip tin)
- What is metformin and sitagliptin (Janumet)?
- What are the possible side effects of metformin and sitagliptin (Janumet)?
- What is the most important information I should know about metformin and sitagliptin (Janumet)?
- What should I discuss with my health care provider before taking metformin and sitagliptin (Janumet)?
- How should I take metformin and sitagliptin (Janumet)?
- What happens if I miss a dose (Janumet)?
- What happens if I overdose (Janumet)?
- What should I avoid while taking metformin and sitagliptin (Janumet)?
- What other drugs will affect metformin and sitagliptin (Janumet)?
- Where can I get more information?
What is metformin and sitagliptin (Janumet)?
Metformin and sitagliptin are oral diabetes medicines that help control blood sugar levels.
Metformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines. Sitagliptin works by regulating the levels of insulin your body produces after eating.
The combination of metformin and sitagliptin is used to treat type 2 diabetes. This medication is not for treating type 1 diabetes.
Metformin and sitagliptin may also be used for purposes not listed in this medication guide.
Janumet 100 mg-50 mg
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Janumet 500 mg-50 mg
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What are the possible side effects of metformin and sitagliptin (Janumet)?
This medication may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or irregular heart rate, dizziness, or feeling very weak or tired.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
- pancreatitis - severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, fast heart rate;
- urinating less than usual or not at all;
- feeling short of breath (even with mild exertion) swelling or rapid weight gain; or
- severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Less serious side effects may include:
- diarrhea, constipation, mild nausea, upset stomach;
- headache, weakness, back pain, joint or mucle pain; or
- cold symptoms such as runny or stuffy nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the Janumet (sitagliptin metformin hcl) Side Effects Center for a complete guide to possible side effects
What is the most important information I should know about metformin and sitagliptin (Janumet)?
You should not use this medication if you are allergic to metformin (Glucophage) or sitagliptin (Januvia), if you have liver or kidney disease, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).
Some people develop lactic acidosis while taking metformin. Early symptoms may get worse over time and this condition can be fatal. Get emergency medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or uneven heart rate, dizziness, or feeling very weak or tired.
If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you will need to temporarily stop taking metformin and sitagliptin.
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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