Januvia (Sitagliptin Phosphate) Patient Information: How Should I Take the Drug at RxList

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May 27, 2012

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Oral Diabetes Prescription Medications »

What are oral diabetes medications and how do they work?

Insulin is a hormone produced by cells in the pancreas called beta cells. Insulin helps the body use blood glucose (a type of sugar) for energy. People with type 2 diabetes do not make enough insulin and/or their bodies do not respond well to it, leading to elevated blood sugar levels. Oral diabetes medications bring blood sugar levels into the normal range through a variety of ways.

For what conditions are diabetes pills used?

Oral diabetes medications are only used to treat type 2 or non-insulin-dependent diabetes. Patients with type 1 diabetes are dependent on insulin for their treatment.

Are there differences among types of oral diabetes medications?

Medications that increase insulin production

The earliest oral diabetes drugs were the sulfonylureas. These work by stimulating the pancreas to produce more insu...

Read the Oral Diabetes Prescription Medications article »

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Januvia Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking sitagliptin (Januvia)?

Do not use this medication if you are allergic to sitagliptin, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use sitagliptin:

kidney disease (or if you are on dialysis); or
a history of pancreatitis.

FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Your name may need to be listed on a sitagliptin pregnancy registry when you start using this medication.

It is not known whether sitagliptin passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Sitagliptin should not be given to a child younger than 18 years old without a doctor's advice.

How should I take sitagliptin (Januvia)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger or smaller amounts, or take it for longer than recommended by your doctor. Your doctor may occasionally change your dose to make sure you get the best results from this medication.

You may take this medicine with or without food. Follow your doctor's instructions.

Sitagliptin is only part of a complete program of treatment that also includes diet, exercise, weight control, and possibly other medications. It is important to use this medicine regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

To be sure this medication is helping your condition, your blood will need to be tested on a regular basis. Your kidney function may also need to be tested. It is important that you not miss any scheduled visits to your doctor.

Your medication needs may change if you become sick or injured, if you have a serious infection, or if you have any type of surgery. Your doctor may want you to stop taking sitagliptin for a short time if any of these situations affect you.

Store sitagliptin at room temperature away from moisture, heat, and light.

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