"Miriam E. Tucker
Medscape Medical News
The US Food and Drug Administration has approved the empagliflozin/linagliptin combination Glyxambi (Boehringer Ingelheim/Eli Lilly) as adjunctive treatment to diet and "...
Jenadueto Patient Information Including Side Effects
Brand Names: Jentadueto
Generic Name: linagliptin and metformin (Pronunciation: LIN a GLIP tin and met FOR min)
- What is linagliptin and metformin (Jenadueto)?
- What are the possible side effects of linagliptin and metformin (Jenadueto)?
- What is the most important information I should know about linagliptin and metformin (Jenadueto)?
- What should I discuss with my healthcare provider before taking linagliptin and metformin (Jenadueto)?
- How should I take linagliptin and metformin (Jenadueto)?
- What happens if I miss a dose (Jenadueto)?
- What happens if I overdose (Jenadueto)?
- What should I avoid while taking linagliptin and metformin (Jenadueto)?
- What other drugs will affect linagliptin and metformin (Jenadueto)?
- Where can I get more information?
What is linagliptin and metformin (Jenadueto)?
Linagliptin and metformin are oral diabetes medicines that help control blood sugar levels. Metformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines. Linagliptin works by regulating the levels of insulin your body produces after eating.
The combination of linagliptin and metformin is used to treat type 2 diabetes. This medication is not for treating type 1 diabetes.
Linagliptin and metformin may also be used for purposes not listed in this medication guide.
What are the possible side effects of linagliptin and metformin (Jenadueto)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
This medication may cause lactic acidosis (a build-up of lactic acid in the body, which can be fatal). Lactic acidosis can start slowly and get worse over time. Get emergency medical help if you have even mild symptoms of lactic acidosis, such as:
- muscle pain or weakness;
- numb or cold feeling in your arms and legs;
- trouble breathing;
- feeling dizzy, light-headed, tired, or very weak;
- stomach pain, nausea with vomiting; or
- slow or uneven heart rate.
Stop using this medicine and call your doctor at once if you have a serious side effect such as:
- swelling, rapid weight gain; or
- severe pain in your upper stomach spreading to your back, nausea and vomiting, and fast heart rate.
Less serious side effects may include:
- cough, sore throat
- sinus pain, stuffy nose;
- upset stomach, diarrhea; or
- weight gain.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Read the Jenadueto (linagliptin and metformin hydrochloride) Side Effects Center for a complete guide to possible side effects
What is the most important information I should know about linagliptin and metformin (Jenadueto)?
Do not use this medication if you are allergic to linagliptin (Onglyza) or metformin (Actoplus Met, Avandamet, Fortamet, Glucophage, Riomet), if you have kidney disease, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).
Before you take linagliptin and metformin, tell your doctor if you have liver disease, a serious infection, heart disease, a history of pancreatitis, if you have recently had a heart attack, or if you are over 80 years old and have not recently had your kidney function checked.
If you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you will need to temporarily stop taking linagliptin and metformin.
Some people develop lactic acidosis while taking metformin. Early symptoms may get worse over time and this condition can be fatal. Get emergency medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or uneven heart rate, dizziness, or feeling very weak or tired.
Additional Jenadueto Information
- Jenadueto Drug Interactions Center: linagliptin-metformin oral
- Jenadueto Side Effects Center
- Jenadueto FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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