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There is no known antidote for JEVTANA overdose. Anticipated complications of overdose include exacerbation of adverse reactions such as bone marrow suppression and gastrointestinal disorders.
In case of overdose, the patient should be kept in a specialized unit where vital signs, chemistry and particular functions can be closely monitored. Patients should receive therapeutic G-CSF as soon as possible after discovery of overdose. Other appropriate symptomatic measures should be taken, as needed.
JEVTANA should not be used in patients with neutrophil counts of ≤ 1,500/mm³.
JEVTANA is contraindicated in patients who have a history of severe hypersensitivity reactions to cabazitaxel or to other drugs formulated with polysorbate 80.
Last reviewed on RxList: 10/16/2012
This monograph has been modified to include the generic and brand name in many instances.
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