In this Article

• What is cabazitaxel (Jevtana)?
• What are the possible side effects of cabazitaxel (Jevtana)?
• What is the most important information I should know about cabazitaxel (Jevtana)?
• What should I discuss with my health care provider before receiving cabazitaxel (Jevtana)?
• How is cabazitaxel given (Jevtana)?
• What happens if I miss a dose (Jevtana)?
• What happens if I overdose (Jevtana)?
• What should I avoid while receiving cabazitaxel (Jevtana)?
• What other drugs will affect cabazitaxel (Jevtana)?
• Where can I get more information?

What should I discuss with my health care provider before receiving cabazitaxel (Jevtana)?

You should not use this medication if you are allergic to cabazitaxel, or if you have:

• liver disease;
• low white blood cell counts; or
• an allergy to any medicine that contains polysorbate 80.

To make sure you can safely receive cabazitaxel, tell your doctor if you have ever had a severe allergic reaction to any medication.

FDA pregnancy category D. Do not use cabazitaxel if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.

It is not known whether cabazitaxel passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are receiving cabazitaxel.

Serious side effects may be more likely in older adults receiving cabazitaxel.

How is cabazitaxel given (Jevtana)?

Cabazitaxel is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Cabazitaxel must be given slowly, and the IV infusion can take about 1 hour to complete.

Cabazitaxel is usually given once every 3 weeks. You will most likely take prednisone by mouth every day throughout your cabazitaxel treatment. Follow your doctor's dosing instructions very carefully.

Do not stop taking prednisone without your doctor's advice, or you could have unpleasant side effects caused by cabazitaxel. Tell your doctor if you have missed any doses or have stopped taking prednisone for any reason.

About 30 minutes before you receive cabazitaxel, you may be given other medications to help prevent certain side effects.

Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice.

To make sure this medication is helping your condition and not causing harmful effects, your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests. Do not miss any follow-up visits to your doctor.

Your doctor may tell you to check your temperature at home throughout your treatment with cabazitaxel.

Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while receiving cabazitaxel, which can lead to a serious electrolyte imbalance.