"Nov. 7, 2012 -- Drinking black tea may help protect against type 2 diabetes, but more study is needed to confirm an association.
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- Clinician Information:
Juvisync Patient Information including If I Miss a Dose
In this Article
- What is simvastatin and sitagliptin (Juvisync)?
- What are the possible side effects of simvastatin and sitagliptin (Juvisync)?
- What is the most important information I should know about simvastatin and sitagliptin (Juvisync)?
- What should I discuss with my healthcare provider before taking simvastatin and sitagliptin (Juvisync)?
- How should I take simvastatin and sitagliptin (Juvisync)?
- What happens if I miss a dose (Juvisync)?
- What happens if I overdose (Juvisync)?
- What should I avoid while taking simvastatin and sitagliptin (Juvisync)?
- What other drugs will affect simvastatin and sitagliptin (Juvisync)?
- Where can I get more information?
What happens if I miss a dose (Juvisync)?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose (Juvisync)?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking simvastatin and sitagliptin (Juvisync)?
Grapefruit and grapefruit juice may interact with simvastatin and lead to potentially dangerous effects. Do not drink more than 1 quart of grapefruit juice daily.
Avoid eating foods that are high in fat or cholesterol. Simvastatin will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan.
Avoid drinking alcohol. It can lower your blood sugar and may increase your risk of liver damage while taking this medicine.
What other drugs will affect simvastatin and sitagliptin (Juvisync)?
Tell your doctor about all other medications you use, especially:
- colchicine (Colcrys);
- digoxin (Lanoxin);
- a blood thinner such as warfarin (Coumadin, Jantoven);
- fenofibric acid (Fibricor, Trilipix), or fenofibrate (Antara, Fenoglide, Lipofen, Lofibra, Tricor, Triglide);
- antifungal medication such as voriconazole (Vfend);
- medicines that contain niacin (Advicor, Niaspan, Niacor, Simcor, Slo-Niacin, and others); or
- any other "statin" medication such as atorvastatin (Lipitor, Caduet), fluvastatin (Lescol), lovastatin (Altoprev, Mevacor), pravastatin (Pravachol), rosuvastatin (Crestor), or other medication that contains simvastatin (Simcor, Vytorin).
Although sitagliptin is not as likely to cause hypoglycemia (low blood sugar) as some other oral diabetes medications, tell your doctor if you are taking any other drugs that can potentially lower blood sugar, such as:
- probenecid (Benemid);
- some nonsteroidal anti-inflammatory drugs (NSAIDs);
- aspirin or other salicylates (including Pepto-Bismol);
- sulfa drugs (Bactrim, Septra, Sulfatrim, SMX-TMP, and others);
- a monoamine oxidase inhibitor (MAOI);
- beta-blockers (Tenormin and others); or
- an oral diabetes medication such as glipizide (Glucotrol, Metaglip), glimepiride (Amaryl, Avandaryl, Duetact), glyburide (DiaBeta, Micronase, Glucovance), and others.
This list is not complete and other drugs may interact with simvastatin and sitagliptin. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about simvastatin and sitagliptin.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2012 Cerner Multum, Inc. Version: 1.02. Revision date: 11/23/2011.
Your use of the content provided in this service indicates that you have read,understood and agree to the End-User License Agreement,which can be accessed by clicking on this link.
Additional Juvisync Information
- Juvisync Drug Interactions Center: sitagliptin-simvastatin oral
- Juvisync Side Effects Center
- Juvisync FDA Approved Prescribing Information including Dosage
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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