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Kaletra Capsules

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Kaletra Capsules

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Kaletra Capsules Patient Information including If I Miss a Dose

What happens if I miss a dose (Kaletra Capsules)?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose (Kaletra Capsules)?

Seek emergency medical attention if you think you have used too much of this medication. An overdose of lopinavir and ritonavir oral liquid could be fatal to a child.

What should I avoid while taking lopinavir and ritonavir (Kaletra Capsules)?

If you take lopinavir and ritonavir liquid and you also take didanosine, take the didanosine at least 1 hour before or 2 hours after you take lopinavir and ritonavir liquid.

Lopinavir and ritonavir oral liquid contains a large portion of alcohol. Avoid drinking alcohol while using this medicine. Tell your doctor if you also take metronidazole (Flagyl) or disulfiram (Antabuse), which can cause severe nausea and vomiting when taken with lopinavir and ritonavir liquid.

Taking this medication will not prevent you from passing HIV to other people through unprotected sex or sharing of needles. Talk with your doctor about safe methods of preventing HIV transmission during sex, such as using a condom and spermicide. Sharing drug or medicine needles is never safe, even for a healthy person.

What other drugs will affect lopinavir and ritonavir (Kaletra Capsules)?

Many drugs can interact with lopinavir and ritonavir. Below is just a partial list. Tell your doctor if you are using:

  • fluticasone (Advair, Flonase, Flovent);
  • rifabutin (Mycobutin);
  • itraconazole (Sporanox) or ketoconazole (Nizoral);
  • an antidepressant such as trazodone (Desyrel) and others;
  • a blood thinner such as warfarin (Coumadin);
  • a calcium channel blocker such as amlodipine (Caduet, Lotrel, Norvasc), diltiazem (Tiazac, Cartia, Dilacor), felodipine (Plendil), nifedipine (Procardia, Adalat), or verapamil (Calan, Covera, Isoptin, Verelan);
  • cholesterol-lowering medicine such as atorvastatin (Lipitor), or rosuvastatin (Crestor);
  • drugs that weaken the immune system, such as cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), or tacrolimus (Prograf);
  • heart rhythm medications such as amiodarone (Cordarone) or quinidine (Quinaglute, Quinidex);
  • other HIV /AIDS medicine such as atazanavir (Reyataz), efavirenz (Sustiva), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), saquinavir (Invirase), and others;
  • insulin or diabetes medication you take by mouth;
  • medicines to treat erectile dysfunction, such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra); or
  • seizure medications such as carbamazepine (Carbatrol, Tegretol), phenobarbital (Luminal, Solfoton), or phenytoin (Dilantin).

This list is not complete and there are many other medicines that can interact with lopinavir and ritonavir. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Where can I get more information?

Your pharmacist can provide more information about lopinavir and ritonavir.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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