"NEW YORK (Reuters Health) - Antiretroviral (ART) combinations containing the recently approved tenofovir alafenamide prodrug offer similar effectiveness and tolerability to those of combinations containing tenofovir disoproxil fumarate, according"...
Kaletra Tablets Patient Information including How Should I Take
In this Article
- What is lopinavir and ritonavir (Kaletra Tablets)?
- What are the possible side effects of lopinavir and ritonavir (Kaletra Tablets)?
- What is the most important information I should know about lopinavir and ritonavir (Kaletra Tablets)?
- What should I discuss with my healthcare provider before taking lopinavir and ritonavir (Kaletra Tablets)?
- How should I take lopinavir and ritonavir (Kaletra Tablets)?
- What happens if I miss a dose (Kaletra Tablets)?
- What happens if I overdose (Kaletra Tablets)?
- What should I avoid while taking lopinavir and ritonavir (Kaletra Tablets)?
- What other drugs will affect lopinavir and ritonavir (Kaletra Tablets)?
- Where can I get more information?
What should I discuss with my healthcare provider before taking lopinavir and ritonavir (Kaletra Tablets)?
You should not use this medication if you are allergic to it.
Life-threatening side effects may occur if you take lopinavir and ritonavir with alfuzosin (Uroxatral), cisapride (Propulsid), lovastatin (Mevacor, Altoprev, Advicor), simvastatin (Zocor, Simcor, Vytorin), St. John's wort, pimozide (Orap), midazolam (Versed) or triazolam (Halcion), rifampin (Rimactane, Rifadin, Rifater, Rifamate), sildenafil (Revatio for pulmonary arterial hypertension), or an ergot medicine such as D.H.E. 45, Ergomar, Cafergot, Ergotrate, Methergine, Migergot, or Migranal.
To make sure you can safely take lopinavir and ritonavir, tell your doctor if you have any of these other conditions:
- liver disease (especially hepatitis B or C);
- heart disease or a heart rhythm disorder;
- a personal or family history of "Long QT Syndrome";
- pancreas problems;
- low levels of potassium in your blood;
- a bleeding disorder such as hemophilia;
- high cholesterol or triglyceride levels in your blood; or
- if you have ever used a protease inhibitor in the past.
FDA pregnancy category C. It is not known whether this medication will harm an unborn baby. HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.
Lopinavir and ritonavir can make birth control pills or patches less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking lopinavir and ritonavir.
Women with HIV or AIDS should not breast-feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.
Do not give this medication to a child younger than 14 days old without medical advice. Premature infants should not receive the medication until it has been 14 days after their original due date.
How should I take lopinavir and ritonavir (Kaletra Tablets)?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label, especially when giving the medicine to a child.
Do not crush, chew, or break a lopinavir and ritonavir tablet. Swallow the pill whole. Kaletra tablets may be taken with or without food.
Kaletra liquid should be taken with food. Measure the liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.
To be sure this medication is helping your condition, your blood may need to be tested often. Your liver function may also need to be tested. Visit your doctor regularly.
Store the liquid medicine in the refrigerator or at room temperature, away from heat or moisture. If you store the medicine at room temperature you must use it within 60 days.
Store the tablets at room temperature, away from heat and moisture. Keep the pills in their original container with the cap tightly closed.
Additional Kaletra Tablets Information
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Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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